Gilley, Rebecca
Kidger, Andrew M. https://orcid.org/0000-0002-3808-0582
Neill, Graham
Morrison, Eve
Severson, Paul https://orcid.org/0009-0008-6762-6557
Byrne, Dominic P.
Kenneth, Niall S. https://orcid.org/0000-0001-8528-1021
Bollag, Gideon
Zhang, Chao
Maia de Oliveira, Taiana https://orcid.org/0000-0003-3231-8112
Eyers, Patrick A. https://orcid.org/0000-0002-9220-2966
Bayliss, Richard https://orcid.org/0000-0003-0604-2773
Masson, Glenn R. https://orcid.org/0000-0002-1386-4719
Cook, Simon J. https://orcid.org/0000-0001-9087-1616
Article History
Received: 9 August 2024
Accepted: 10 October 2025
First Online: 17 November 2025
Competing interests
: PS, GB and CZ were paid employees of Plexxikon Inc. TMO is a paid employee of AstraZeneca. The initial stages of this work were supported by a sponsored research collaboration in SJC’s laboratory funded by Plexxikon Inc; this paid AK’s salary; SJC received no remuneration from Plexxikon. The remaining authors declare no competing interests.