Martin, Peter R. https://orcid.org/0000-0003-2048-421X
Nieminuszczy, Jadwiga https://orcid.org/0000-0003-4672-9684
Kozik, Zuza
Jakub, Nihal
Kowalski, Szymon
Lecot, Maxime https://orcid.org/0009-0008-9957-3066
Vorhauser, Julia
Lane, Karen A. https://orcid.org/0000-0003-0560-1502
Kanellou, Alexandra
Mansfeld, Jörg https://orcid.org/0000-0002-0562-8206
Pearl, Laurence H.
Oliver, Antony W. https://orcid.org/0000-0002-2912-8273
Downs, Jessica A. https://orcid.org/0000-0002-6600-849X
Choudhary, Jyoti S. https://orcid.org/0000-0003-0881-5477
Day, Matthew https://orcid.org/0000-0001-7218-867X
Niedzwiedz, Wojciech https://orcid.org/0000-0002-8518-6304
Funding for this research was provided by:
RCUK | Biotechnology and Biological Sciences Research Council (BB/T009608/1)
RCUK | MRC | Medical Research Foundation (MR/X018547/1)
Cancer Research UK (A24881)
Cancer Research UK (CRUK RRCOER-Jun24/100006)
Cancer Research UK (RCCSCF-Nov22/100001)
Cancer Research UK (C7905/A25715)
Cancer Research UK (A24881)
Cancer Research UK (C302/A24386)
Cancer Research UK (C302/A24386)
Cancer Research UK (C7905/A25715)
Cancer Research UK (C302/A24386)
Cancer Research UK (A24881)
Cancer Research UK (CRUK RRCOER-Jun24/100006)
Wellcome Trust (223745/Z/21/Z)
Wellcome Trust (223745/Z/21/Z)
Royal Society (RG\R2\232017)
Article History
Received: 29 October 2024
Accepted: 10 October 2025
First Online: 27 November 2025
Competing interests
: P.M., M.D., and W.N. are inventors on a filed patent application (GB 2415863.6 and GB2418894.8) covering targeting of the SLX4-TOPBP1 interaction for cancer therapy. The other authors declare no competing interests.