Uchigashima, Motokazu https://orcid.org/0000-0002-0878-2233
Iguchi, Risa https://orcid.org/0000-0002-4839-0808
Fujii, Kazuma
Shiku, Kaito https://orcid.org/0009-0000-9675-9502
Kumar, Pratik https://orcid.org/0000-0002-9516-0212
Liu, Xinyi
Isogai, Mari
Hoshino, Chiaki
Abe, Manabu https://orcid.org/0000-0001-8534-2138
Nozumi, Motohiro https://orcid.org/0000-0001-5972-2719
Okamura, Yosuke
Igarashi, Michihiro https://orcid.org/0000-0003-1474-3385
Sakimura, Kenji
Bise, Ryoma
Lavis, Luke D. https://orcid.org/0000-0002-0789-6343
Mikuni, Takayasu https://orcid.org/0000-0002-9769-9369
Funding for this research was provided by:
Japan Agency for Medical Research and Development (JP19dm0207080, JP21wm0525014, and JP24wm0625117)
MEXT | JST | Precursory Research for Embryonic Science and Technology (JPMJPR16F9)
Human Frontier Science Program (CDA00043/2019-C)
Uehara Memorial Foundation (N/A)
MEXT | Japan Society for the Promotion of Science (JP20K21461, JP20H03349, JP20H05918, JP23K18160, and JP24K02130)
MEXT | Japan Science and Technology Agency (JPMJFR231M)
Kowa Life Science Foundation (N/A)
Article History
Received: 21 March 2025
Accepted: 24 October 2025
First Online: 11 November 2025
Competing interests
: The authors declare no competing interests.