Fujioka, Toshifumi
Nishimura, Tamako https://orcid.org/0000-0001-9015-377X
Kawana, Hiroki
Hirosawa, Koichiro M. https://orcid.org/0000-0003-0170-3755
Yamakawa, Renta
Sapili, Hani
Oono-Yakura, Kayoko
Nakagawa, Ryoya
Inoue, Takanari https://orcid.org/0000-0002-7957-7624
Nureki, Osamu https://orcid.org/0000-0003-1813-7008
Suzuki, Kenichi G. N. https://orcid.org/0000-0002-8436-5757
Suetsugu, Shiro https://orcid.org/0000-0002-4612-0628
Funding for this research was provided by:
MEXT | Japan Society for the Promotion of Science (JP21H05047)
MEXT | Japan Society for the Promotion of Science (JP20KK0341)
MEXT | Japan Society for the Promotion of Science (JP20H03252)
MEXT | Japan Society for the Promotion of Science (JP24H01286)
MEXT | Japan Society for the Promotion of Science (25K22505)
MEXT | Japan Society for the Promotion of Science (JP17K07427)
MEXT | Japan Society for the Promotion of Science (JP20K06625)
MEXT | Japan Society for the Promotion of Science (JP23H02476)
MEXT | Japan Society for the Promotion of Science (24K09778)
MEXT | JST | Core Research for Evolutional Science and Technology (JPMJCR1863)
MEXT | JST | Core Research for Evolutional Science and Technology (JPMJCR24B3)
MEXT | JST | Core Research for Evolutional Science and Technology (JPMJCR24B3)
MEXT | JST | Core Research for Evolutional Science and Technology (JPMJCR24B3)
Uehara Memorial Foundation
Takeda Science Foundation
2021 NAIST University Fellowships for the Creation of Innovation in Science and Technology
MEXT | Japan Science and Technology Agency (JPMJFR2413)
NSF | BIO | Division of Molecular and Cellular Biosciences (000819255)
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (R35GM149329)
Article History
Received: 10 February 2025
Accepted: 4 November 2025
First Online: 8 December 2025
Competing interests
: T.F., T.N., H.K., and S.S. have submitted a patent application to the Japan Patent Office pertaining to the dimerization-induced protein delivery by the protrusion-derived EVs aspects of this work (Application Number (2024)218454). The remaining authors declare no competing interests.