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In silico docking yields small molecule negative allosteric modulators targeting the core of Frizzled 7

Crossref DOI link: https://doi.org/10.1038/s41467-025-67147-z

Published Online: 2025-12-14

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Scharf, Magdalena M. https://orcid.org/0000-0002-3305-3956
Kinsolving, Julia https://orcid.org/0000-0002-0431-8222
Grätz, Lukas

Voss, Jan Hendrik https://orcid.org/0000-0003-0595-4607
Carrasco-Busturia, David https://orcid.org/0000-0003-1588-338X
Forsberg, Björn https://orcid.org/0000-0002-6247-4063
Kolb, Peter https://orcid.org/0000-0003-4089-614X
Schulte, Gunnar https://orcid.org/0000-0002-2700-7013
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Text and Data Mining valid from 2025-12-14

Version of Record valid from 2025-12-15
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Article History

Received: 26 June 2025

Accepted: 24 November 2025

First Online: 14 December 2025

Competing interests

: The authors declare no competing interests.