Howe, Laurence J.
Aulchenko, Yurii S. https://orcid.org/0000-0002-7899-1575
Davey Smith, George https://orcid.org/0000-0002-1407-8314
Davies, Neil M. https://orcid.org/0000-0002-2460-0508
Esparza-Gordillo, Jorge
Johnson, Toby
Liu, Jimmy Z. https://orcid.org/0000-0002-8379-5480
Richardson, Tom G.
Sanseau, Philippe
Scott, Robert A. https://orcid.org/0000-0003-3634-3016
Seaton, Daniel D.
Sharma, Ashwini https://orcid.org/0000-0001-7883-7888
Cortes, Adrian https://orcid.org/0000-0002-3490-007X
Article History
Received: 22 October 2024
Accepted: 25 November 2025
First Online: 13 December 2025
Competing interests
: LJH, YSA, AC, JEG, TJ, JZL, TGR, PS, RAS, DDS, and AS are all employees and/or stockholders of GSK. GDS reports Scientific Advisory Board Membership for Bristol Myers Squibb, Relation Therapeutics and Insitro. The remaining authors declare no competing interests.