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Authors
Spiga, Martina https://orcid.org/0000-0003-0038-6233
Potenza, Alessia https://orcid.org/0000-0003-0298-7315
Magnani, Zulma
Beretta, Stefano
Camisa, Barbara
Conte, Laura
Airaghi, Alessia
Mohammadi, Neda
Perani, Laura https://orcid.org/0000-0001-8616-3377
Doglioni, Claudio https://orcid.org/0000-0002-4969-5216
Ponzoni, Maurilio https://orcid.org/0000-0002-0055-325X
Sanvito, Francesca https://orcid.org/0000-0002-4046-8420
Balestrieri, Chiara https://orcid.org/0000-0001-7362-3530
Sergi Sergi, Lucia
Botrugno, Oronza A. https://orcid.org/0000-0002-2568-9815
Giovannoni, Giulio
Tonon, Giovanni https://orcid.org/0000-0003-2973-5038
Abbati, Danilo https://orcid.org/0000-0001-8517-7937
Iozzi, Chiara
Reichert, Maximilian https://orcid.org/0000-0002-8611-5639
Algul, Hana
Pocaterra, Arianna
Fiumara, Martina https://orcid.org/0009-0007-5934-9273
Ferrari, Samuele https://orcid.org/0000-0003-1122-1231
Ugolini, Alessia
Grometto, Alice
Di Lullo, Giulia
Sitia, Giovanni https://orcid.org/0000-0003-1024-9128
Belfiori, Giulio
Protti, Maria Pia
Ostuni, Renato https://orcid.org/0000-0003-0460-3426
Mondino, Anna
Reni, Michele
Crippa, Stefano
Falconi, Massimo https://orcid.org/0000-0001-9654-7243
Naldini, Luigi https://orcid.org/0000-0002-7835-527X
Ruggiero, Eliana https://orcid.org/0000-0002-2954-8278
Bonini, Chiara https://orcid.org/0000-0002-0772-1674
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Funding
Funding for this research was provided by:
Associazione Italiana per la Ricerca sul Cancro (AIRC5x1000 22737)
Associazione Italiana per la Ricerca sul Cancro (AIRC-IG 18458)
Associazione Italiana per la Ricerca sul Cancro (ID 29914 - 2023)
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Article History
Received: 15 April 2025
Accepted: 26 November 2025
First Online: 8 January 2026
Competing interests
: CBo has been member of Advisory Board and Consultant for Intellia, TxCell, Novartis, GSK, Allogene, Kite/Gilead, Kiadis, Evir, Janssen, Genyo, Epsilen, and received research support from Intellia Therapeutics. MS, AP, ER, and CBo are inventors in the patent WO2025/003481 including TCRs and sgRNAs employed in this work. AP, ZM, ER, CBo are inventors on different patents on cancer immunotherapy and genetic engineering. L.N. is founder of, quota holder and consultant for GeneSpire and Epsilen Bio/Chroma Medicine. All other authors declare no competing interests.
