Launspach, Michael https://orcid.org/0000-0001-5337-5605
Macos, Julia https://orcid.org/0009-0008-9196-3975
Afzal, Shoaib https://orcid.org/0009-0009-5490-6098
Hohmann, Janik https://orcid.org/0009-0001-5374-1350
Appis, Marc L. https://orcid.org/0000-0002-0155-1918
Pilgram, Maximilian https://orcid.org/0009-0002-3423-5249
Beez, Stefanie
Ohlendorf, Emily
van der Ven, Casper F. T. https://orcid.org/0000-0001-7947-6105
Lachiheb, Chahrazad
Töws, Karin
Andersch, Lena
Jens, Marvin https://orcid.org/0000-0002-6660-8743
Zirngibl, Felix https://orcid.org/0000-0003-1764-4841
Kath, Jonas https://orcid.org/0000-0001-7721-7978
Stecklum, Maria https://orcid.org/0009-0001-7951-5730
Rodriguez-Fos, Elias https://orcid.org/0000-0002-2555-0178
Anders, Kathleen
Wagner, Dimitrios L. https://orcid.org/0000-0002-2189-3579
Henssen, Anton G. https://orcid.org/0000-0003-1534-778X
Kühn, Ralf https://orcid.org/0000-0003-1694-9803
Eggert, Angelika
Künkele, Annette https://orcid.org/0000-0002-8406-5412
Article History
Received: 1 April 2025
Accepted: 25 November 2025
First Online: 9 December 2025
Change Date: 30 January 2026
Change Type: Update
Change Details: In the version of the article initially published, the text Parts of this research were carried out within the scientific framework of the DFG-funded Collaborative Research Center CRC1588 (493872418). K.T. was supported as a junior clinician scientist within Collaborative Research Center CRC1588 (493872418)" was missing from the Acknowledgements section and has now been added to the HTML and PDF versions of the article.
Competing interests
: M.L. reports in-kind support (reagents and services) related to CRISPR-Cas gene editing and digital PCR from QIAGEN. This support did not influence the design, execution, analysis, or interpretation of the present study. D.L.W.’s laboratory at Charité has received in-kind reagents/services related to CRISPR–Cas gene editing from Integrated DNA Technologies (IDT) and GenScript Inc. None of the companies or intellectual property described influenced the design, execution, or interpretation of this study. Unrelated to this work, D.L.W. is named as an inventor on patent applications related to genome editing and cell therapies and is a co-founder of TCBalance Biopharmaceuticals GmbH. All other authors declare no competing interests.