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Authors
Meng, Qinglong
Benckendorff, Caecilie https://orcid.org/0009-0009-1495-8424
Morrill, Charlotte
Zhuo, Ying
Egerström, Annette https://orcid.org/0009-0001-3145-5978
Ní Cheallaigh, Aisling
Derrington, Sasha R.
Obexer, Richard https://orcid.org/0000-0002-4940-3543
Ortmayer, Mary
Levy, Colin W.
Finnigan, James D. https://orcid.org/0000-0002-8514-784X
Charnock, Simon J.
Turner, Nicholas J. https://orcid.org/0000-0002-8708-0781
Miller, Gavin J. https://orcid.org/0000-0001-6533-3306
Lovelock, Sarah L. https://orcid.org/0000-0002-4584-3189
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Funding
Funding for this research was provided by:
Research Councils UK (MR/T041722/1)
RCUK | Medical Research Council (MR/W029324/1)
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Article History
Received: 7 May 2025
Accepted: 28 November 2025
First Online: 17 December 2025
Competing interests
: S.L.L. and Q.M. have filed a patent application to the UK Patent office (application number GB 2517296.6) describing our biocatalytic method of NTP synthesis and engineered PhoC sequences. S.L.L. has filed an international patent describing the application of a polymerase and endonuclease V cascade for production of therapeutic oligonucleotides (WO2023/041931). The remaining authors declare no competing interests.
