Hajjar, Mohammad https://orcid.org/0000-0002-9478-7216
Maola, Victoria A.
Lee, Joy J. https://orcid.org/0009-0005-4471-7649
Holguin, Manuel J. https://orcid.org/0000-0002-2830-5303
Quijano, Riley N.
Nguyen, Kalvin K.
Ho, Katherine L. https://orcid.org/0009-0008-6933-0178
Medina, Jenny V.
Botello-Cornejo, Elionel https://orcid.org/0009-0009-0974-5803
Barpuzary, Bhawna https://orcid.org/0009-0007-1288-0120
Chim, Nicholas https://orcid.org/0000-0003-2274-5305
Chaput, John C. https://orcid.org/0000-0003-1393-135X
Funding for this research was provided by:
National Science Foundation (2433788)
Article History
Received: 25 July 2025
Accepted: 4 December 2025
First Online: 19 December 2025
Competing interests
: J.C., V.M., and the University of California-Irvine have filed a patent application (PCT/US24/11595) on the composition and activity of the 10–92 TNA polymerase. No financial competing interests are declared. The remaining authors declare no competing interests.