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Authors
Chuong, Melisa
Thompson, Deborah
Weale, Michael E. https://orcid.org/0000-0003-4593-1186
Riveros-Mckay, Fernando
Samani, Nilesh J. https://orcid.org/0000-0002-3286-8133
Wells, Daniel
Plagnol, Vincent
McVean, Gil
Ashley, Euan A. https://orcid.org/0000-0001-9418-9577
Donnelly, Peter
Harrison, Seamus
O’Sullivan, Jack W. https://orcid.org/0000-0003-3629-2546
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Article History
Received: 20 January 2025
Accepted: 17 December 2025
First Online: 21 January 2026
Competing interests
: M.C., D.T., M.E.W., F.R-M., D.W., V.P., G.M., P.D., and S.H. are current or former employees of Genomics Ltd, and own or have owned shares or stock options in the company. G.M. and P.D. are also partners in Peptide Groove LLP. E.A.A. reports advisory board fees from SequenceBio, Foresite Labs, Pacific Biosciences, and Versant Ventures. E.A.A. has ownership interest in Personalis, Deepcell, Svexa, Candela, Parameter Health, Saturnus Bio, outside the submitted work. E.A.A. is a non-executive director of AstraZeneca and Svexa. E.A.A. receives collaborative research support from Illumina, Pacific Biosciences, Oxford Nanopore, Cache, Cellsonics, outside the submitted work. JWO’S is supported by the AHA Postdoctoral fellowship and ACC postdoctoral fellowship and has had consultancy relationships with Google AI, Google Deepmind and Foresite Labs (outside the current work).
