Huff, Amanda L.
Haldar, S. Daniel
Gergis, Alexander A.
Wang, Hejia Henry https://orcid.org/0000-0003-1836-7567
Danilova, Ludmila https://orcid.org/0000-0003-2813-3094
Heumann, Thatcher
Berg, Maureen
Wang, Yuxuan
Andaloori, Lalitya
Hernandez, Alexei https://orcid.org/0000-0002-6044-2631
Longway, Gabriella
Barrett, Benjamin
Zhu, Zirui
Davis-Marcisak, Emily
Thoburn, Christopher https://orcid.org/0000-0001-7743-9183
Leatherman, James https://orcid.org/0000-0002-1721-2128
Mitchell, Sarah
Lee, Jae W.
Shu, Daniel H.
Konig, Maximillian F. https://orcid.org/0000-0001-5045-5255
Mog, Brian J.
Montagne, Janelle https://orcid.org/0000-0002-8113-1373
Coyne, Erin M. https://orcid.org/0000-0002-0393-6600
Bever, Katherine
Baretti, Marina
Yarchoan, Mark https://orcid.org/0000-0003-4401-0748
Anders, Robert A.
Kagohara, Luciane T. https://orcid.org/0000-0003-1706-0950
Laheru, Daniel https://orcid.org/0000-0001-6646-0200
Thomas, Amy M.
Durham, Jennifer
Nauroth, Julie M.
Lu, Jiayun
Wang, Hao https://orcid.org/0000-0001-6489-6940
Fertig, Elana J.
Ho, Won Jin https://orcid.org/0000-0003-2644-5086
Azad, Nilofer S.
Jaffee, Elizabeth M. https://orcid.org/0000-0003-3841-6549
Zaidi, Neeha https://orcid.org/0000-0002-0094-0049
Funding for this research was provided by:
Lustgarten Foundation (PI: Jaffee)
Lustgarten Foundation (PI: Jaffee)
EIF | Stand Up To Cancer
U.S. Department of Health & Human Services | NIH | National Cancer Institute (P01CA247886)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (K08CA248624)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (P01CA247886)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (F32CA271470-01)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (R50 CA243627)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (P50CA062924)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (P01CA247886)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (P50CA062924)
Article History
Received: 25 June 2025
Accepted: 22 December 2025
First Online: 10 February 2026
Competing interests
: E.M.J. reports other support from Abmeta, other support from Adventris, personal fees from Achilles, personal fees from DragonFly, personal fees from Parker Institute and CPRIT, personal fees from Surge and HDTbio, grants from Lustgarten, grants from Genentech, personal fees from Mestag, personal fees from Medical Home Group, grants from BMS, and grants from Break Through Cancer outside the submitted work. Dr. Jaffee is the Dana and Albert “Cubby” Broccoli Professor of Oncology. ALH is a paid consultant of Adventris Pharmaceuticals Inc. SDH reports consulting for Sift Biosciences and HMP Omnimedia; research support from Summit Therapeutics, Shionogi, and Bristol Myers Squibb; and travel/honoraria from DAVA Oncology. NZ receives research support from Bristol Myers Squibb, is a consultant for Genentech, and receives other support from Adventris Pharmaceuticals. NSA is a paid consultant for Mirati and QED. Dr. Azad receives institutional funding from Agios, Inc., Array, Atlas, Bayer HealthCare, BMS, Celgene, Debio, Eli Lilly and Company, EMD Serono, Incyte Corporation, Intensity, Merck & Co., Inc. and Taiho Pharmaceuticals Co., Ltd. Dr. Azad participates on advisory boards for Incyte, QED, and Glaxo Smith Kline. EJF is on the scientific advisory board of Resistance Bio, received consulting fees from Mestag Therapeutics and Merck, and receives research funding from Abbvie, Inc. ‘WJH reports patent royalties from Rodeo/Amgen, received grants from Sanofi and NeoTX (to Johns Hopkins), and speaking/travel honoraria from Exelixis and Standard BioTools. N.Z., E.M.J., A.L.H., M.Y., A.A.G., and E.F.J. have current filed patents related to the KRAS peptides and/or TCRs. The remaining authors declare no competing interests.