Zhang, Zicong https://orcid.org/0000-0003-1444-5054
Georgakopoulos-Soares, Ilias https://orcid.org/0000-0003-3641-1488
Bourque, Guillaume https://orcid.org/0000-0002-3933-9656
Ahituv, Nadav https://orcid.org/0000-0002-7434-8144
Inoue, Fumitaka https://orcid.org/0000-0003-0657-434X
Funding for this research was provided by:
Japan Agency for Medical Research and Development (JP24gm7010002)
Ministry of Education, Culture, Sports, Science and Technology (JP24K02004)
Ministry of Education, Culture, Sports, Science and Technology (JP24K18101)
MEXT | Japan Society for the Promotion of Science
U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute (1R21HG010683)
U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute (1UM1HG009408)
U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute (1UM1HG011966)
Article History
Received: 17 June 2025
Accepted: 7 January 2026
First Online: 14 January 2026
Competing interests
: F.I. receives funding from Relation Therapeutics. N.A. is a Cofounder and on the scientific advisory board of Regel Therapeutics Inc. N.A. received funding from BioMarin Pharmaceutical Inc. The remaining authors declare no competing interests.