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Combinatory differentiation of human induced pluripotent stem cells generates functional thymic epithelium driving dendritic cell and CD4/CD8 T cell development

Crossref DOI link: https://doi.org/10.1038/s41467-026-68675-y

Published Online: 2026-01-23

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Provin, Nathan

d’Arco, Manon https://orcid.org/0009-0002-7239-4435
Le Bozec, Antoine

Kervagoret, Erwan

Bruneau, Alexandre

Brusselle, Lucas

Fourgeux, Cynthia https://orcid.org/0000-0002-3330-7530
Poschmann, Jeremie https://orcid.org/0000-0002-9613-5297
Hulin, Philippe

Maminirina, Pierre

Baron, Olivier

Saulquin, Xavier

Guillonneau, Carole

David, Laurent https://orcid.org/0000-0003-3594-0353
Giraud, Matthieu https://orcid.org/0000-0002-1208-9677
Funding

Funding for this research was provided by:

Agence Nationale de la Recherche (ANR-19-RAR4-0011-05)

National Organization for Rare Disorders (22001)

“la Région Pays de la Loire” RFI Bioregate grant (ThymIPS) "SATT Ouest Valorisation"
License Information

Text and Data Mining valid from 2026-01-23

Accepted Manuscript valid from 2026-01-23
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Article History

Received: 5 May 2024

Accepted: 14 January 2026

First Online: 23 January 2026

Competing interests

: The authors declare no competing interests.

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