Melore, Schuyler M. https://orcid.org/0000-0002-0694-6388
McRoberts Amador, Christian D. https://orcid.org/0000-0001-5595-1450
Hamilton, Marisa C.
Gersbach, Charles A. https://orcid.org/0000-0003-1478-4013
Reddy, Timothy E. https://orcid.org/0000-0002-7629-061X
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute (RM1 HG011123)
U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute (UM1 HG012053)
U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute (UM1 HG012053)
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01 MH125236)
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01 MH125236)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (R01 CA289574)
Article History
Received: 5 September 2024
Accepted: 23 January 2026
First Online: 12 February 2026
Competing interests
: Duke University has submitted a patent application to the US PTO pertaining to the novel dCas12a fusion proteins and hybrid crRNA array aspects of this work (application number PCT/US2023/076920) for which T.E.R., S.M.M. and C.A.G. are inventors. The remaining authors declare no competing interests.