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Combining xQTL and genome-wide association studies from diverse populations improves druggable gene discovery

Crossref DOI link: https://doi.org/10.1038/s41467-026-69236-z

Published Online: 2026-02-14

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Lorincz-Comi, Noah

Song, Wenqiang

Chen, Xin

Paz, Isabela Rivera

Hou, Yuan

Zhou, Yadi

Xu, Jielin

Martin, William https://orcid.org/0000-0003-0616-0462
Barnard, John https://orcid.org/0000-0003-2403-8268
Pieper, Andrew A.

Haines, Jonathan L. https://orcid.org/0000-0002-4351-4728
Chung, Mina K.

Cheng, Feixiong https://orcid.org/0000-0002-1736-2847
Funding

Funding for this research was provided by:

U.S. Department of Health Human Services | NIH | National Institute on Aging (R01AG066707)

U.S. Department of Health Human Services | NIH | National Institute on Aging (R01AG084250)

U.S. Department of Health Human Services | NIH | National Institute on Aging (R01AG076448)

U.S. Department of Health Human Services | NIH | National Institute on Aging (R01AG082118)

U.S. Department of Health Human Services | NIH | National Institute on Aging (R01AG092462)

U.S. Department of Health Human Services | NIH | National Institute on Aging (R01AG092591)

U.S. Department of Health Human Services | NIH | National Institute on Aging (RF1AG082211)

U.S. Department of Health Human Services | NIH | National Institute on Aging (R33AG083003)

U.S. Department of Health Human Services | NIH | National Heart, Lung, and Blood Institute (P01HL158501)
License Information

Text and Data Mining valid from 2026-02-14

Accepted Manuscript valid from 2026-02-14
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Article History

Received: 19 May 2025

Accepted: 22 January 2026

First Online: 14 February 2026

Competing interests

: All authors declare no competing financial and non-financial interests.

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