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Intestinal interleukin-22 enhances GLP-1 production via the STAT3 pathway to improve glucose homeostasis during high-fat diet induced obesity in a study with male mice

Crossref DOI link: https://doi.org/10.1038/s41467-026-69734-0

Published Online: 2026-02-21

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Kim, Chae-Won

Ahn, Jae-Hee

Lee, Bo Ra

Kim, Hong Min https://orcid.org/0000-0003-0046-4449
Han, Youngjoo

Jeong, Jae-Hyeon

Cho, Jaewon

Jeong, Hyunjin

Kim, Dae-Joon

Kim, Seong-Eun

Kim, Jeon-Kyung https://orcid.org/0000-0001-6746-6364
Lee, Yu-Bin

Kim, Su Min

Yoo, Hye Hyun https://orcid.org/0000-0001-8282-852X
Lee, Eun Hye

Seo, Su Ryeon

Ha, Kyung Bong

Lee, Eun Soo

Kweon, Mi-Na https://orcid.org/0000-0003-2916-2524
Kim, Hong Pyo

Chang, Sun-Young https://orcid.org/0000-0001-7336-9245
Chung, Choon Hee

Ko, Hyun-Jeong https://orcid.org/0000-0002-3844-928X
Funding

Funding for this research was provided by:

National Research Foundation of Korea (NRF-2020R1A5A8019180)

Ministry of Science and ICT (MSIT) of Korea
License Information

Text and Data Mining valid from 2026-02-21

Accepted Manuscript valid from 2026-02-21
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Article History

Received: 26 May 2021

Accepted: 2 February 2026

First Online: 21 February 2026

Competing interests

: The authors declare no competing interests.

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