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Computation and resource efficient genome-wide association analysis for large-scale imaging studies

Crossref DOI link: https://doi.org/10.1038/s41467-026-69816-z

Published Online: 2026-02-28

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Jiang, Zhiwen https://orcid.org/0000-0001-8841-618X
Stein, Jason https://orcid.org/0000-0003-4829-0513
Li, Tengfei https://orcid.org/0000-0001-6142-3865
Fang, Ethan

Li, Yun https://orcid.org/0000-0002-9275-4189
Sullivan, Patrick https://orcid.org/0000-0002-6619-873X
Zhu, Hongtu https://orcid.org/0000-0002-6781-2690
Funding

Funding for this research was provided by:

U.S. Department of Health & Human Services | NIH | National Institute on Aging (R01AG085581)

U.S. Department of Health & Human Services | NIH | National Institute on Aging (RF1AG082938)

U.S. Department of Health & Human Services | NIH | National Institute on Aging (U01AG088667)

U.S. Department of Health & Human Services | NIH | National Institute on Aging (R01AG098697)

U.S. Department of Health & Human Services | NIH | National Institute on Aging (R01AG085581)

U.S. Department of Health & Human Services | NIH | National Institute on Aging (RF1AG082938)

U.S. Department of Health & Human Services | NIH | National Institute on Aging (U01AG088667)

U.S. Department of Health & Human Services | National Institutes of Health (R01MH136055)

U.S. Department of Health & Human Services | National Institutes of Health (1U01AG088667-01)

U.S. Department of Health & Human Services | National Institutes of Health (R01MH136055)

U.S. Department of Health & Human Services | National Institutes of Health (K01AG095286)

U.S. Department of Health & Human Services | National Institutes of Health (R21HD120911)

U.S. Department of Health & Human Services | National Institutes of Health (U01HG011720)

U.S. Department of Health & Human Services | National Institutes of Health (R01MH125236)

Center for Hierarchical Manufacturing, National Science Foundation (DMS-2434666)

U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (P50HD103573)
License Information

Text and Data Mining valid from 2026-02-28

Version of Record valid from 2026-04-09
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Article History

Received: 5 September 2025

Accepted: 9 February 2026

First Online: 28 February 2026

Competing interests

: P.S. reports the following potentially competing financial interests (2024): Neumora Therapeutics (advisory committee, shareholder). To the best of his knowledge, these are unrelated to this paper/project. The remaining authors declare no competing interests.

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