Song, Jinyang
Qi, Lei https://orcid.org/0000-0002-8491-8999
Li, Yongyue
Zhang, Xue
He, Yushu
Zhang, Zhengshi
He, Dongfang
Gu, Mengjun
Guan, Yuyao
Fang, Hao
Hou, Xuben https://orcid.org/0000-0002-8346-9001
Li, Zengpeng https://orcid.org/0009-0004-7463-0790
Wang, Wei https://orcid.org/0000-0002-6346-2216
Article History
Received: 13 June 2025
Accepted: 11 February 2026
First Online: 24 February 2026
Competing interests
: The authors declare the following competing interests: Shandong University has filed patent application No. 202512010140.8 relating to the AI-designed scaffold protein constructs (Trimbody) described in this study. W.W., Z.L., and J.S. are listed as inventors on this application. The remaining authors declare no competing interests.