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Single-engineered-residue solvation perturbations regulate global protein architecture and function

Crossref DOI link: https://doi.org/10.1038/s41467-026-70155-2

Published Online: 2026-03-10

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Liu, Yingya https://orcid.org/0000-0002-2833-0541
Zhai, Jihang

Cao, Shanshan https://orcid.org/0009-0007-0035-1096
Guo, Huiying

Zhang, Hengwei https://orcid.org/0000-0003-2723-5638
Song, Bo https://orcid.org/0000-0001-5600-106X
Guo, Jiajia https://orcid.org/0000-0002-6118-8241
Men, Dong https://orcid.org/0000-0003-1190-9570
He, Xiao https://orcid.org/0000-0002-4199-8175
Li, Di https://orcid.org/0000-0003-1674-0110
License Information

Text and Data Mining valid from 2026-03-10

Accepted Manuscript valid from 2026-03-10
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Article History

Received: 7 August 2025

Accepted: 20 February 2026

First Online: 10 March 2026

Competing interests

: The authors declare no competing interests.