Hanno, Yoko https://orcid.org/0009-0006-2066-3276
Nakanishi, Moe
Takase, Akinori
Nomura, Jun https://orcid.org/0000-0003-0817-2643
Tanaka, Masami https://orcid.org/0000-0001-5782-0278
Iida, Yumi
Tanaka, Masayuki https://orcid.org/0000-0002-8682-8719
Hosokawa, Hiroyuki https://orcid.org/0000-0002-9592-2889
Ito, Masatoshi https://orcid.org/0000-0003-2665-0020
Mikami, Katsunaka
Hozumi, Katsuto
Miyoshi, Goichi https://orcid.org/0000-0002-1872-6278
Takumi, Toru https://orcid.org/0000-0001-7153-266X
Iijima, Takatoshi https://orcid.org/0009-0007-1841-3419
Funding for this research was provided by:
MEXT | Japan Society for the Promotion of Science (15K14355)
MEXT | Japan Society for the Promotion of Science (20K22913)
MEXT | Japan Society for the Promotion of Science (21K07327)
MEXT | Japan Society for the Promotion of Science (24K10716)
Article History
Received: 16 April 2025
Accepted: 23 February 2026
First Online: 30 March 2026
Competing interests
: All authors have seen and approved the manuscript, and the authors declare that they have no conflicts of interest with the contents of this article. K.M. has received personal fees from Shionogi & Co., Ltd., Sumitomo Pharma Co., Ltd., Takeda Pharmaceutical Co., Ltd., Lundbeck Japan K.K., EA Pharma Co., Ltd., and Otsuka Pharmaceutical Co., Ltd. These financial relationships are fully disclosed in accordance with the International Committee of Medical Journal Editors guidelines. These funding sources are unrelated to the present study and did not influence the design, execution, analysis, interpretation, or reporting of this research.