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Authors
Rodrigo-Brenni, Monica C.
Komen, Jasper C.
Hamza, Ghaith M.
Bohin, Natacha https://orcid.org/0000-0001-8571-9898
Adomavicius, Tomas
Andres, Angelo
Blaho, Stefan
Börjesson, Ulf
Collie, Gavin W. https://orcid.org/0000-0002-0406-922X
De Donatis, Gian Marco
Eisele, Frederik https://orcid.org/0000-0001-9995-5816
Gao, Ning https://orcid.org/0000-0003-1605-4137
Gohlke, Andrea
Grebner, Christoph https://orcid.org/0000-0001-5301-1078
Gustafsson, Frida
Hock, Andreas
Kankkonen, Cecilia
Kumar, Praveen https://orcid.org/0000-0002-7818-671X
Leonard, Emilyanne https://orcid.org/0000-0002-1866-4193
Li, Xin
Macdonald, Ruth
Madeyski-Bengtson, Katja
Miele, Eric
Nevin, Philip
Overman, Jeroen
Pachl, Fiona
Pathe, Claudio
Perry, Matthew W. D.
Phillips, Christopher https://orcid.org/0000-0001-6569-9025
Pike, Andy https://orcid.org/0000-0001-6078-7501
Purvis, Ian
Rasmusson, Timothy
Regan, Sophie
Reilly, Linda
Rose, Jonathan
Storer, R. Ian
Wang, Jingwen
Zhai, Xiang
Michaelides, Iacovos N.
Moreau, Kevin
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Article History
Received: 6 December 2024
Accepted: 25 February 2026
First Online: 25 March 2026
Competing interests
: The authors declare the following competing interests: all the authors are or have been employed by AstraZeneca or Pharmaron. The synthesis of CRBN ligands and their associated CRBN binding data for compounds 2, 3, 4, 5, 6, 8 and 12 are reported in patent number: PCT/EP2021/076752 (WO2022069520); status of application: national phase applications pending; patent applicant: Astrazeneca AB; Inventors: Borjesson, Ulf; Perry, Matthew William Dampier; Grebner, Christoph; Michaelides, Iacovos Neal; Hayhow, Thomas George Christopher; Kettle, Jason Grant; Collie, Gavin William; Storer, Robert Ian; Bagal, Sharanjeet Kaur; Fallan, Charlene.
