Takei, Shota https://orcid.org/0009-0000-3810-8269
Yamasaki, Satoshi https://orcid.org/0000-0003-4722-9315
Yamaguchi, Ou
Mouri, Atsuto
Shiono, Ayako https://orcid.org/0000-0001-6546-3864
Miura, Yu
Hashimoto, Kosuke
Imai, Hisao https://orcid.org/0000-0003-3097-4255
Kaira, Kyoichi
Ichiki, Yoshinobu
Nitanda, Hiroyuki
Sakaguchi, Hirozo
Hishida, Tomoyuki
Horimoto, Katsuhisa
Kagamu, Hiroshi https://orcid.org/0000-0003-4523-8517
Funding for this research was provided by:
Japan Agency for Medical Research and Development (19ae0101074h0001)
MEXT | Japan Society for the Promotion of Science (23K24341)
Article History
Received: 30 May 2025
Accepted: 10 March 2026
First Online: 28 March 2026
Competing interests
: HK is listed as an inventor on a patent application filed by Saitama Medical University that incorporates the discoveries described in this manuscript. HK has received grant support from Boehringer-Ingelheim, Inc. The other authors declare no competing interests.