Zheng, Neil S.
Huang, Shi
Annis, Jeffrey
Master, Hiral
Full, Kelsie M.
Brittain, Evan L. https://orcid.org/0000-0001-5843-3392
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (R21 HL172038)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (R61/R33 HL158941)
U.S. Department of Health & Human Services | U.S. Food and Drug Administration (R01 FD007627)
Article History
Received: 29 September 2025
Accepted: 26 March 2026
First Online: 7 April 2026
Competing interests
: E.L.B has received research funds unrelated to this work from United Therapeutics and Anumana and unrestricted funds for research from Google. The All of Us Research Program was not involved in the design and conduct of the study; collection, management, and analysis of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication. To ensure privacy of participants, data used for this study was accessed and available to approved researchers only following registration, completion of ethics training, and attestation of a data use agreement through the All of Us Research Workbench platform, which can be accessed via . The remaining authors declare no competing interests.