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SARS-CoV-2 infection during the first trimester leads to profound immune dysregulation at the maternal-fetal interface despite limited virus detection in placental tissues

Crossref DOI link: https://doi.org/10.1038/s41467-026-71770-9

Published Online: 2026-04-13

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Liu, Xian-Xian

Shen, Xuejuan

Cui, Xinyuan https://orcid.org/0000-0002-0556-7191
Chen, Xiaoyuan

Jin, Tengchuan https://orcid.org/0000-0002-1395-188X
Cao, Hua-Bin

Lu, Xiaoman

Liu, Mengyao

Hu, Li-Li

Chen, Yiting

Chen, Xiao-Qing

Zeng, Yang

Gan, Yingde

Ou-Yang, Xin

Lei, Jie

Liu, Fa-Ying

Chen, Fangting

Zou, Yang https://orcid.org/0000-0002-7335-8850
Shen, Yongyi
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (U24A20363)

Natural Science Foundation of Jiangxi Province (20224ACB206006)
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Text and Data Mining valid from 2026-04-13

Version of Record valid from 2026-06-10
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Article History

Received: 24 October 2025

Accepted: 30 March 2026

First Online: 13 April 2026

Competing interests

: The authors declare no competing interests.

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