Shilliday, Fiona https://orcid.org/0000-0002-9275-0604
Gancedo-Rodrigo, Miguel https://orcid.org/0000-0003-0287-4337
George, Ginto
Aibara, Shintaro
Adhikari, Santosh
Ashraf, Syedah Neha
Barrey, Evelyne J.
Centrella, Paolo A.
Crowther, Damian https://orcid.org/0000-0001-7791-1396
Dickson, Paige https://orcid.org/0000-0002-9196-2031
Gikunju, Diana
Guié, Marie-Aude
Guilinger, John P.
Gunnarsson, Anders
Harding, Heather P. https://orcid.org/0000-0002-7359-7974
Hupp, Christopher D.
Jetson, Rachael
Keefe, Anthony D. https://orcid.org/0000-0003-4548-2835
Kim, JeeSoo Monica
Lewis, Richard J. https://orcid.org/0000-0001-9404-8520
Maia de Oliveira, Taiana https://orcid.org/0000-0003-3231-8112
Le-Marshall, Jennifer
Narayanan, Usha
Nugai, Katherine A.
Petrović, Dušan https://orcid.org/0000-0002-1834-7358
Rivers, Emma
Ron, David https://orcid.org/0000-0002-3014-5636
Stringfellow, Daisy https://orcid.org/0009-0003-1267-706X
Syson, Karl
Ward, Lewis https://orcid.org/0000-0002-5087-6305
Yeoman, John T. S.
Yu, Yan
Zhang, Ying https://orcid.org/0000-0001-7263-9143
Zyryanova, Alisa
Baker, David J. https://orcid.org/0000-0001-6799-2161
Breccia, Perla
Linley, John E.
Article History
Received: 13 February 2025
Accepted: 22 April 2026
First Online: 6 May 2026
Competing interests
: F.S., S.A. (S. Aibara), S.N.A., E.J.B., A.G., J.M.K., T.M.O., E.R., L.W. and D.J.B. are employees of AstraZeneca and have stock ownership and/or stock options or interests in the company. D.C. is now an employee of TrimTech Therapeutics. M.G.-R. and S.A. (S. Adhikari) are now employees of Isomorphic Labs. A.Z. is now an employee of Altos. D.P. is now an employee of Novartis Biomedical Research. D. S. is now a student at the University of Nottingham. K.S. is now an employee of Cancer Research Horizons. J. E. L. is now an employee of Dompé. P. B. is now an employee of Astex Pharmaceuticals. P.A.C., P.D., D.G., M-A.G., J.P.G., C.D.H., R.J., A.D.K., J.L.-M., U.N., K.A.N., J.T., S.Y., Y.Y. and Y.Z. are current or former employees of X-Chem Inc. and have stock ownership and/or stock options or interests in the company. D.G. is currently an employee of Bonito Biosciences. C.D.H. is currently an employee of Ipsen. J.L.-M. is currently an employee of Flagship Ventures 106. U.N. is currently an employee of Odyssey Therapeutics. J.T.S.Y is currently an employee of Recludix Pharma. R.J. is now an employee of HitGen. The remaining authors declare no competing interests.