Maiorino, Enrico https://orcid.org/0000-0002-0159-4221
Marzio, Margherita De https://orcid.org/0000-0003-1821-208X
Xu, Zhonghui
Yun, Jeong H. https://orcid.org/0000-0002-4361-8295
Chase, Robert P. https://orcid.org/0000-0003-1183-0619
Hersh, Craig P.
Sin, Don D. https://orcid.org/0000-0002-0756-6643
Weiss, Scott T.
Silverman, Edwin K.
Castaldi, Peter J.
Glass, Kimberly https://orcid.org/0000-0003-4394-5779
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (R01HL155749)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (K01HL166705)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (K25HL168157)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (PO1HL132825)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (R01HL124233)
Article History
Received: 3 January 2024
Accepted: 28 April 2026
First Online: 19 May 2026
Competing interests
: J.H.Y. received consulting fees from Bridge BioTherapeutics. PJC received consulting fees from Verona Pharmaceuticals and research support from Bayer and Sanofi, both outside of this work. In the past three years, EKS received grant support from Bayer and Northpond Laboratories. STW receives royalties from UpToDate and is on the Board of Histolix, a digital pathology company. DDS received honoraria from AstraZeneca and GlaxoSmithKline for delivering educational presentations on COPD. The remaining authors declare no conflicts of interest.