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Single-cell multimodal profiling of pan-cancer cell lines uncovers gene regulatory principles underlying intrinsic cell states and environmental features

Crossref DOI link: https://doi.org/10.1038/s41467-026-75360-7

Published Online: 2026-07-23

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Xu, Zihan https://orcid.org/0009-0008-9317-9279
Ugurbil, Aileen

Kwan, Joshua

Schaefer, Chloe https://orcid.org/0009-0008-2913-9352
Abdulraouf, Abdulraouf

Lu, Ziyu https://orcid.org/0000-0003-4321-2727
Tang, Erting https://orcid.org/0000-0001-5348-799X
Zhou, Wei https://orcid.org/0000-0003-4236-4091
Cao, Junyue https://orcid.org/0000-0003-4097-489X
Funding

Funding for this research was provided by:

U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute (DP2HG012522)

U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute (RM1HG011014)

Melanoma Research Alliance
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Text and Data Mining valid from 2026-07-23

Version of Record valid from 2026-07-23
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Article History

Received: 23 February 2026

Accepted: 29 June 2026

First Online: 23 July 2026

Ethics

Competing interests: EasySci is covered under patent WO 2024/073412 A3, with J.C., W.Z., Z.L., and Z.X. listed as inventors. All other authors declare no competing interests.

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