Jones, Matthew G. https://orcid.org/0000-0002-0363-4493
Weiser, Natasha E. https://orcid.org/0000-0001-9971-2961
Hung, King L. https://orcid.org/0000-0002-3662-4662
Yan, Xiaowei https://orcid.org/0000-0002-4846-8812
Agarwal, Sangya
Luebeck, Jens https://orcid.org/0000-0003-4391-979X
Gnanasekar, Aditi
Zhang, Shu
Wong, Ivy Tsz-Lo https://orcid.org/0000-0002-9761-3422
Tang, Jun
Howitt, Brooke E. https://orcid.org/0000-0002-0309-6680
Curtis, Ellis J.
Yu, Kevin https://orcid.org/0009-0002-1164-1252
Rose, John C. https://orcid.org/0000-0003-1810-4337
Kraft, Katerina
Valiollah Pour Amiri, Valeh
Satpathy, Leena
Bafna, Vineet https://orcid.org/0000-0002-5810-6241
Mischel, Paul S. https://orcid.org/0000-0002-4560-2211
Chang, Howard Y. https://orcid.org/0000-0002-9459-4393
Article History
Received: 9 December 2025
Accepted: 24 July 2026
First Online: 8 August 2026
Ethics
Competing interests: H.Y.C. is an employee and stockholder of Amgen as of Dec. 16, 2024. H.Y.C. is a co-founder of Accent Therapeutics, Boundless Bio, Cartography Biosciences, Orbital Therapeutics, and was an advisor of 10× Genomics, Arsenal Bio, Chroma Medicine, Exai Bio, and Vida Ventures. M.G.J. consults for and holds equity in Tahoe Therapeutics and Factorial Biotechnologies. P.S.M. was a co-founder of Boundless Bio and had equity and consulted for the company. P.S.M. is a co-founder of Alterris Oncology; he has equity and consults, for which he is compensated. V.B. is a co-founder, paid consultant, and scientific advisory board member and has equity interests in Boundless Bio and Abterra. The terms of this arrangement have been reviewed and approved by the University of California, San Diego, in accordance with its conflict-of-interest policies. K.K. is an employee and stockholder of Amgen. S.A. is an employee of Amgen. B.H. has received research support from Cartography, Santa Ana Bio, Link Cell Sciences, and Immunogen. B.H. has received consulting/advisory fees from Cartography, Roche, Leica, Tempus, and AbbVie. V.V.P.A. is a stockholder of Microsoft. The remaining authors declare no competing interests.