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Article History

Received: 17 January 2024

Accepted: 29 October 2024

First Online: 9 November 2024

Competing interests

: The authors declare no competing interests.

: All protocols were approved by the Renmin Hospital of Wuhan University Institutional Review Board (approval no. WDRY2023-K023). Informed consent was waived by the committee. Research records or samples intended for publication will adhere to strict confidentiality standards, excluding any names or other identifying information of the subjects. Subject information, encompassing medical records, clinical examination results, and related data, is uniquely identified by a designated code. Only research doctors and authorized personnel can associate this code with the names of subjects through a checklist, which is securely stored in the research center. The research data is kept at the Clinical Laboratory Center and can be viewed by researchers, research regulatory authorities, and ethics committees. Public reports on the results of this study will not disclose the personal identity of the subjects. Animal studies were conducted in strict accordance with protocols approved by the Animal Experiment Center Renmin Hospital of Wuhan University (approval no. S0272012259A).