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Alternate-day fasting ameliorates α-synuclein pathology and suppresses inflammation via the gut-brain axis in an MPTP-induced subacute mouse model of Parkinson’s disease

Crossref DOI link: https://doi.org/10.1038/s41522-025-00855-y

Published Online: 2025-12-17

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Wang, Zhonglei

Cui, Yueran

Li, Dongpu

Yan, Lili

Zhu, Shihan

Ma, Xiaoming

Lu, Zongzong

Li, Chenfeng

Feng, Juan

Yuan, Wei

He, Xin
Funding

Funding for this research was provided by:

Basic Research Program of Liaoning Province (2022020802-JH2/1015)

Basic Research Program of Liaoning Province (2022020802-JH2/1015)

Basic Research Program of Liaoning Province (2022020802-JH2/1015)

Basic Research Program of Liaoning Province (2022020802-JH2/1015)

Basic Research Program of Liaoning Province (2022020802-JH2/1015)

Basic Research Program of Liaoning Province (2022020802-JH2/1015)

Basic Research Program of Liaoning Province (2022020802-JH2/1015)

Basic Research Program of Liaoning Province (2022020802-JH2/1015)

Basic Research Program of Liaoning Province (2022020802-JH2/1015)

Basic Research Program of Liaoning Province (2022020802-JH2/1015)

Basic Research Program of Liaoning Province (2022020802-JH2/1015)

Shengjing Hospital (345 Talent Project)

Shengjing Hospital (345 Talent Project)

Shengjing Hospital (345 Talent Project)

Shengjing Hospital (345 Talent Project)

Shengjing Hospital (345 Talent Project)

Shengjing Hospital (345 Talent Project)

Shengjing Hospital (345 Talent Project)

Shengjing Hospital (345 Talent Project)

Shengjing Hospital (345 Talent Project)

Shengjing Hospital (345 Talent Project)

Shengjing Hospital (345 Talent Project)

National Natural Science Foundation of china (82271275)

National Natural Science Foundation of china (82271275)

National Natural Science Foundation of china (82271275)

National Natural Science Foundation of china (82271275)

National Natural Science Foundation of china (82271275)

National Natural Science Foundation of china (82271275)

National Natural Science Foundation of china (82271275)

National Natural Science Foundation of china (82271275)

National Natural Science Foundation of china (82271275)

National Natural Science Foundation of china (82271275)

National Natural Science Foundation of china (82271275)
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Text and Data Mining valid from 2025-12-17

Version of Record valid from 2025-12-17
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Article History

Received: 28 January 2025

Accepted: 3 November 2025

First Online: 17 December 2025

Competing interests

: The authors declare no competing interests.

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