Hudeček, Jan http://orcid.org/0000-0003-1071-5686
Voorwerk, Leonie
van Seijen, Maartje
Nederlof, Iris
de Maaker, Michiel
van den Berg, Jose
van de Vijver, Koen K. http://orcid.org/0000-0002-2026-9790
Sikorska, Karolina
Adams, Sylvia
Demaria, Sandra http://orcid.org/0000-0003-4426-0499
Viale, Giuseppe
Nielsen, Torsten O.
Badve, Sunil S. http://orcid.org/0000-0001-8861-9980
Michiels, Stefan
Symmans, William Fraser http://orcid.org/0000-0002-1526-184X
Sotiriou, Christos
Rimm, David L. http://orcid.org/0000-0001-5820-4397
Hewitt, Stephen M.
Denkert, Carsten
Loibl, Sibylle
Loi, Sherene http://orcid.org/0000-0001-6137-9171
Bartlett, John M. S.
Pruneri, Giancarlo
Dillon, Deborah A.
Cheang, Maggie C. U.
Tutt, Andrew
Hall, Jacqueline A. http://orcid.org/0000-0003-0708-1360
Kos, Zuzana
Salgado, Roberto
Kok, Marleen
Horlings, Hugo M. http://orcid.org/0000-0003-4782-8828
,
Hyytiäinen, Aini
Hida, Akira I.
Thompson, Alastair
Lefevre, Alex
Lazar, Alexander J.
Gown, Allen
Lo, Amy
Sapino, Anna
Madabhushi, Anant
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Beck, Andrew H.
Bellizzi, Andrew M.
Guerrero, Angel
Grigoriadis, Anita
Ehinger, Anna
Garrido-Castro, Ana
Vincent-Salomon, Anne
Laenkholm, Anne-Vibeke
Sharma, Ashish
Cimino-Mathews, Ashley
Srinivasan, Ashok
Acs, Balazs
Singh, Baljit
Calhoun, Benjamin
Haibe-Kans, Benjamin
Solomon, Benjamin
Thapa, Bibhusal
Nelson, Brad H.
Gallas, Brandon D.
Castaneda, Carlos
Ballesteros-Merino, Carmen
Criscitiello, Carmen
Boeckx, Carolien
Colpaert, Cecile
Quinn, Cecily
Chennubhotla, Chakra S.
Swanton, Charles
Solinas, Cinzia
Hiley, Crispin
Drubay, Damien
Bethmann, Daniel
Moore, David A.
Larsimont, Denis
Sabanathan, Dhanusha
Peeters, Dieter
Zardavas, Dimitrios
Höflmayer, Doris
Johnson, Douglas B.
Thompson, E. Aubrey
Brogi, Edi
Perez, Edith
ElGabry, Ehab A.
Stovgaard, Elisabeth Specht
Blackley, Elizabeth F.
Roblin, Elvire
Reisenbichler, Emily
Bellolio, Enrique
Balslev, Eva
Chmielik, Ewa
Gaire, Fabien
Andre, Fabrice
Lu, Fang-I
Azmoudeh-Ardalan, Farid
Rojo, Federico
Gruosso, Tina
Ciompi, Francesco
Peale, Franklin
Hirsch, Fred R.
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Acosta Haab, Gabriela
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McArthur, Heather
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Wesseling, Jelle
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Araya, Juan Carlos
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Saeger, Kai
Siziopikou, Kalliopi
Willard-Gallo, Karen
Weber, Karsten
Pogue-Geile, Katherine L.
Steele, Keith E.
Emancipator, Kenneth
AbdulJabbar, Khalid
El Bairi, Khalid
Blenman, Kim R. M.
Allison, Kimberly H.
Korski, Konstanty
Pusztai, Lajos
Comerma, Laura
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Shi, Leming
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van de Vijver, Marc
Balancin, Marcelo Luiz
Dieci, Maria Vittoria
Mathieu, Marie-Christine
Rebelatto, Marlon C.
Piccart, Martine
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Preusser, Matthias
Khojasteh, Mehrnoush
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de Wind, Roland
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De Clercq, Sabine
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Tabbarah, Sami
Souza, Sandra C.
O’Toole, Sandra
Swain, Sandra
Dudgeon, Sarah
Willis, Scooter
Ely, Scott
Kim, Seong-Rim
Bedri, Shahinaz
Irshad, Sheeba
Liu, Shi-Wei
Goel, Shom
Hendry, Shona
Bianchi, Simonetta
Bragança, Sofia
Paik, Soonmyung
Wienert, Stephan
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Luen, Stephen J.
Naber, Stephen
Schnitt, Stuart J.
Sua, Luz F.
Lakhani, Sunil R.
Fineberg, Susan
Soler, Teresa
Gevaert, Thomas
D’Alfonso, Timothy
John, Tom
Sugie, Tomohagu
Kurkure, Uday
Bossuyt, Veerle
Manem, Venkata
Cámara, Vincente Peg
Tong, Weida
Chen, Weijie
Yang, Wentao
Tran, William T.
Wang, Yihong
Yuan, Yinyin
Allory, Yves
Husain, Zaheed
Bago-Horvath, Zsuzsanna
Funding for this research was provided by:
Breast Cancer Research Foundation
Article History
Received: 16 July 2019
Accepted: 18 February 2020
First Online: 12 May 2020
Competing interests
: J.H. is the owner of Slide Score. B.V. L.V., M.v.S., I.N., M.d.M., J.v.d.B., K.K.v.d.V., K.S., S.A., S.D., G.V., S.S.B., S.M., W.F.S., C.S., S.M.H., C.D., S.L., G.P., M.C.U.C., Z.K., and H.M.H. have nothing to disclose. T.O.N. has consulted for Nanostring and received compensation and has intellectual property rights/ownership interests from Bioclassifier LLC, not related to the subject material under consideration and received funding support from the Canadian Cancer Society. D.L.R. reports research funding from AstraZeneca, Cepheid, Navigate BioPharma, NextCure, Lilly, and Ultivue; instrument support from Ventana, Akoya/PerkinElmer, and NanoString; advisory board of Amgen, AstraZeneca, Cell Signaling Technology, Cepheid, Daiichi Sankyo, GSK, Konica/Minolta, Merck, NanoString, PerkinElmer, Ventana, and Ultivue; consultancy for Biocept; honorarium and travel support from BMS; royalties from Rarecyte and is a founder and equity holder of PixelGear. Sh.L. receives research funding to her institution from Novartis, Bristol Meyers Squibb, Merck, Roche-Genentech, Puma Biotechnology, Pfizer, and Eli Lilly, acted as consultant (not compensated) to Seattle Genetics, Pfizer, Novartis, BMS, Merck, AstraZeneca, and Roche-Genentech and acted as consultant (paid to her institution) to Aduro Biotech. J.M.S.B. reports research funding from ThermoFisher, Genoptix, Agendia, NanoString Technologies, Stratifyer GmbH, and Biotheranostics and advisory roles for Insight Genetics, BioNTech AG, Biotheranostics, Pfizer, RNA Diagnostics, and OncoXchange. J.M.S.B. reports the following patents: Methods and Devices for Predicting Anthracycline Treatment Efficacy, US utility (January 2017; 15/325,472; EPO – 15822898.1; Canada – not yet assigned), Systems, Devices and Methods for Constructing and Using a Biomarker, US utility (January 2017; 15/328,108; EPO – 15824751.0; Canada – not yet assigned), Histone gene module predicts anthracycline benefit (October 2016; PCT/CA2016/000247), 95‐Gene Signature of Residual Risk Following Endocrine Treatment (December 2016; PCT/CA2016/000304), Immune Gene Signature Predicts Anthracycline Benefit (December 2016; PCT/CA2016/000305). D.A.D. is on the advisory board and consults for Oncology Analytics Inc., and has consulted for and received travel funds from Novartis for work unrelated to the current manuscript. A.T. reports benefits from ICR’s Inventors Scheme associated with patents for one of PARP inhibitors in BRCA1/2-associated cancers. A.T. also reports Honoraria from Pfizer, Vertex, Prime Oncology, and Artios, honoraria and stock in InBioMotion, honoraria and financial support for research from AstraZeneca, Medivation, Myriad Genetics, and Merck Serono. J.A.H. is the director and owner of Vivactiv Ltd. R.S. reports research funding from Roche, Puma, and Merck; advisory board and consultancy for BMS; travel funding from Roche, Merck, and AstraZeneca, outside the scope of this work. M.K. reports funding to the institute from BMS, Roche and an advisory role for BMS, outside the submitted work.