Pizzamiglio, S.
Blanda, A.
Appierto, V.
Minicozzi, P.
Carnevale, M. G.
De Santis, M. C.
Re, B.
Cortesi, L.
Gasparini, E.
Arpino, G.
Giuliano, M.
Molinaro, V.
Iorio, M. V.
De Cecco, L.
Bertolotti, A.
Brich, S.
Vingiani, Andrea
De Marco, C.
Pruneri, G.
Verderio, P.
Di Cosimo, S.
Funding for this research was provided by:
Ministry of Health, Ricerca Corrente funds
Article History
Received: 7 August 2025
Accepted: 16 November 2025
First Online: 3 December 2025
Competing interests
: G.P.: speaker honoraria/advisory board: ADS Biotec, Exact Sciences, Lilly, Novartis, and Roche; institutional research grant from Roche; L.C.: speaker bureau: AstraZeneca, MSD, Pfizer, Novartis, Gilead, Roche, Daiichi Sankyo; advisory board: AstraZeneca, MSD, Novartis; travel and accommodation expenses from Gilead, Pfizer, Daiichi Sankyo; S.D.C.: “ad hoc” medical monitor for Medica Scientia Innovation Research (MEDSIR), Barcelona (Spain); as well as support for attending meetings and/or travel from Daiichi Sankyo, and participation in an advisory board for Pfizer. M.G.: speaker honoraria/advisory board: AstraZeneca, Daichii Sankyo, Eisai, Exact Sciences, Gilead, Gentili, Lilly, MSD, Novartis, Pfizer, Roche. G.A.: honoraria for lectures, presentations, speaker’s bureaus, manuscript writing or educational events from Roche, Pfizer, Lilly, AstraZeneca, Novartis and Gilead; travel grants from Roche, Lilly, AstraZeneca and Gilead; advisory boards for Roche, Novartis, Lilly, Pfizer, MSD, Dompè, Pierre Fabre, Eisai, Sophos, Epionpharma, Gilead, Seagen, Astra Zeneca and Exact Science. P.V. and S.D.C. are leading the PNRR-POC-2023-12378113 project, founded by the European Union - Next Generation EU – PNRR M6C2 – Investimento 2.1 Valorizzazione e potenziamento della ricerca biomedical del SSN, titled “A Composite Assay for HER2- Positive Early-Stage Breast Cancer Management”. The authors declare no competing interests.