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Authors
Khor, Chiea Chuen
Ong, Whee Sze
Lim, Elaine Hsuen
Chatelut, Etienne
Chen, Sylvia
Muerdter, Thomas E.
Abraham, Jean E.
Sutiman, Natalia
Lim, Joanne Siok Liu
Lee, Sze Sing
Arellano, Cecile
Li, Zheng
Sim, Kar Seng
Eccles, Diana M.
Tapper, William J.
Maishman, Tom
Zgheib, Nathalie K.
Winter, Stefan
Ganchev, Boian
Dorling, Leila
Guo, Qi
Caldas, Carlos
Earl, Helena M.
Hiller, Louise
Dunn, Janet
Ng, Raymond Chee Hui
Yap, Yoon Sim
Wong, Mabel
Wong, Fuh Yong
Wong, Nan Soon
Ang, Peter Cher Siang
Dent, Rebecca
Krippl, Peter
Langsenlehner, Uwe
Langsenlehner, Tanja
Tfayli, Arafat
Schaeffeler, Elke
Eichelbaum, Michel
Hamann, Ute
Fasching, Peter A.
Beckmann, Matthias W.
Dalenc, Florence
White-Koning, Melanie
Brauch, Hiltrud B.
Schroth, Werner
Renner, Wilfried
Schwab, Matthias
Thomas, Fabienne
Chowbay, Balram
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Funding
Funding for this research was provided by:
National Research Foundation of Singapore (NRF-NRFI2018-01)
Biomedical Research Council, Agency for Science, Technology and Research, Singapore
the Robert Bosch Foundation, Stuttgart, Germany and German Federal Ministry of Education and Research (BMBF; 01ZP0502, 01EK1509A)
The Deutsche Foschungsgemeinschaft (DFG, German Research Foundation) under Germany's Excellence Strategy (EXC 2180–390900677 and DFG grants SCHR 1323/2-1 and MU 1727/2-1)
German Cancer Consortium (DKTK), Partner Site Tübingen, 72074 Tübingen
The Interfaculty Center for Pharmacogenomics and Drug Research (ICEPHA), University of Tuebingen
National Medical Research Council (NMRC/1159/2008, NMRCB1011, NRFCG1516, NMRCG13163 and NMRC/CIRG/1423/2015, MOH-000377)
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Article History
Received: 3 December 2025
Accepted: 3 March 2026
First Online: 20 March 2026
Competing interests
: Carlos Caldas is a member of the AstraZeneca External Science Panel and has received research grants (administered by the University of Cambridge) from AstraZeneca, Genentech, Roche and Servier. Helena M. Earl has received research grants from Roche and Sanofi-Aventis (administered by Cambridge University Hospital Trust), honoraria and travel expenses from Daiichi-Sankyo, Astra Zeneca, Pfizer, Amgen and Prime Oncology all outside the submitted work. Jean E. Abraham has received research grants from AstraZeneca (administered by the Cambridge University Hospital Trust and the University of Cambridge, Dept of Oncology), honoraria and travel expenses from Astra Zeneca and Pfizer all outside the submitted work. All other authors declare no competing interests.
