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Simulated microgravity-driven mechanical unloading rescues PIEZO1-overexpression-induced growth plate ossification and retards adolescent idiopathic scoliosis

Crossref DOI link: https://doi.org/10.1038/s41526-026-00604-1

Published Online: 2026-05-04

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Chen, Fei

Chen, Shuqing

Jing, Xingzhi

Peng, Fushuai

Du, Yukun

Li, Jianyi

Fan, Yuanyuan

Cui, Zichen

Gu, Guanghui

Zhang, Han

Dong, Jun

Li, Tao

Xi, Yongming
Funding

Funding for this research was provided by:

Scientific Research Projects of Shandong Medical Association (YXH2024YS019)

Taishan Scholars Program of Shandong Province (NO. tstp20250511)

Space Science and Application Project of China Space Station Application and Development Program (KJZ-YY-NSM0619)
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Text and Data Mining valid from 2026-05-04

Accepted Manuscript valid from 2026-05-04
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Article History

Received: 31 October 2025

Accepted: 22 April 2026

First Online: 4 May 2026

Competing interests

: The authors declare no competing interests.

: The corresponding author has received consent for publication.

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