Chapman, Sarah
Dale, Peter
Svedsater, Henrik
Stynes, Gillian
Vyas, Nicola
Price, David http://orcid.org/0000-0002-9728-9992
Horne, Rob
Article History
Received: 23 June 2017
Revised: 26 September 2017
Accepted: 13 October 2017
First Online: 14 November 2017
Competing interests
: S.C. has undertaken consultancy work for University College London spin-out company Spoonful of Sugar, including work commissioned by GlaxoSmithKline. H.S. is a GlaxoSmithKline employee and holds GlaxoSmithKline stocks. P.D. and G.S. are former GlaxoSmithKline employees and hold GlaxoSmithKline stocks. N.V. is an employee of Healthcare Research Worldwide, commissioned by GlaxoSmithKline to conduct the original market research survey. D.P. declares the following conflicts of interest: board membership with Aerocrine, Almirall, Amgen, AstraZeneca, Boehringer Ingelheim, Chiesi, Meda, Mundipharma, Napp, Novartis and Teva Pharmaceuticals; consultancy with Almirall, Amgen, AstraZeneca, Boehringer Ingelheim, Chiesi, GlaxoSmithKline, Meda, Mundipharma, Napp, Novartis, Pfizer and Teva Pharmaceuticals; grants and unrestricted funding for investigator-initiated studies (conducted through Research in Real-Life Ltd and Observational and Pragmatic Research Institute Pte Ltd) from the UK National Health Service, British Lung Foundation, Aerocrine, AKL Ltd, Almirall, AstraZeneca, Boehringer Ingelheim, Chiesi, Eli Lilly, GlaxoSmithKline, Meda, Merck, Mundipharma, Napp, Novartis, Orion, Pfizer, Respiratory Effectiveness Group, Takeda, Teva Pharmaceuticals and Zentiva; payments for lectures/speaking from Almirall, AstraZeneca, Boehringer Ingelheim, Chiesi, Cipla, GlaxoSmithKline, Kyorin, Meda, Merck, Mundipharma, Novartis, Pfizer, Skyepharma, Takeda and Teva Pharmaceuticals; payment for manuscript preparation from Mundipharma and Teva Pharmaceuticals; patents (planned, pending or issued) from AKL Ltd; payment for the development of educational materials from GlaxoSmithKline and Novartis; stock/stock options from AKL Ltd, which produces phytopharmaceuticals; ownership of 80% of Research in Real Life Ltd, 75% of the social enterprise Optimum Patient Care Ltd and 75% of Observational and Pragmatic Research Institute Pte Ltd; payment for travel/accommodations/meeting expenses from Aerocrine, Boehringer Ingelheim, Mundipharma, Napp, Novartis and Teva Pharmaceuticals; funding for patient enrolment or completion of research from Almirral, Chiesi, Teva Pharmaceuticals and Zentiva; and peer review for grant committees of the Medical Research Council (2014), Efficacy and Mechanism Evaluation programme (2012), HTA (2014). R.H. is a member of the Medical Innovation Academic Consortium, the academic arm of CASMI. R.H has undertaken speaker engagements with honoraria from the following organisations AbbVie, Amgen, Biogen, Idec, Gilead Sciences, GlaxoSmithKline, Janssen, Pfizer, Roche, Shire Pharmaceuticals, MSD, Astellas, AstraZeneca, DRSU, Novartis, Universitatsklinikum Hamburg-Eppendorf, Teva Pharmaceuticals. Professor Horne was supported by Asthma UK Centre for Applied Research (AUKCAR) and the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care (CLAHRC) North Thames at Bart's Health NHS Trust. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health.