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Article History

Received: 30 June 2021

Accepted: 22 December 2021

First Online: 10 March 2022

Competing interests

: I.O. has received travel grants, consulting fees, speaking fees or research grants from AstraZeneca, Bial, Boehringer Ingelheim, Chiesi, GSK, Mundipharma, Novartis, Teva, Sanofi, MSD and Puretech; I.O. is a researcher supported by the “Pla Estratègic de Recerca i Innovació en Salut PERIS)” 2016–2020 (SLT008/18/00108;G60594009). M.B. has received speaker fees from CSL Behring, Grifols, Menarini, GSK and Boehringer Ingelheim, consulting fees from GSK, Novartis and Boehringer Ingelheim. X.M. has received fees as a speaker, scientific advisor, or participant of clinical studies from AstraZeneca, Boehringer Ingelheim, Chiesi, Faes, GSK, Menarini, Mundipharma, Novartis, and Teva. M. Miravitlles has received speaker fees from AstraZeneca, Boehringer Ingelheim, Chiesi, Cipla, Menarini, Rovi, Bial, Zambon, CSL Behring, Grifols and Novartis, consulting fees from AstraZeneca, Boehringer Ingelheim, Chiesi, GSK, Bial, Gebro Pharma, CSL Behring, Laboratorios Esteve, Ferrer, Mereo Biopharma, Verona Pharma, Teva, pH Pharma, Novartis and Grifols and research grants from Grifols. X.F. has received speaking fees from AstraZeneca, Chiesi, GSK, Mundipharma and Teva. M. Monteagudo, A.N., and J.O. declare no competing interests.

: The study was conducted in compliance with local legislation for observational trials and it was approved by the IDIAP Jordi Gol Clinical Research Ethics Committee. As this is an observational study based on a database that uses anonymised patient records, patient informed consent is not applicable.