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Lavoie, Suzie https://orcid.org/0000-0001-8372-2399
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Addamo, Lauren
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Cahill, John
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Dzafic, Ilvana
Ebdrup, Bjørn H.
Izyurov, Igor
Jarcho, Johanna
Jenni, Raoul https://orcid.org/0000-0001-6479-5381
Jo, Anna https://orcid.org/0000-0002-9820-5826
Kerins, Sarah
Lee, Clarice
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Mayol-Troncoso, Rocio https://orcid.org/0000-0002-6421-8768
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Parvaz, Muhammad
Pogarell, Oliver https://orcid.org/0000-0001-6455-4190
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Rabin, Rachel https://orcid.org/0000-0002-6530-0288
Roalf, David R.
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Shaik, Riaz
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Thompson, Judy L.
Tso, Ivy https://orcid.org/0000-0002-0984-1186
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Zhou, Juan Helen https://orcid.org/0000-0002-0180-8648
Addington, Jean https://orcid.org/0000-0002-8298-0756
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Langbein, Kerstin
Mamah, Daniel
Mittal, Vijay A. https://orcid.org/0000-0001-9017-5119
Nordentoft, Merete
Pearlson, Godfrey D.
Perez, Jesus
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Pasternak, Ofer
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Coleman, Michael J.
Dwyer, Dominic https://orcid.org/0000-0003-3949-5867
Nunez, Angela
Tamayo, Zailyn
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McGorry, Patrick D.
Bearden, Carrie E. https://orcid.org/0000-0002-8516-923X
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Woods, Scott W. https://orcid.org/0000-0002-3103-5228
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,
Light, Gregory A.
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (U01MH124639, U24MH124629)
Wellcome Trust (220664/Z/20/Z)
Foundation for the National Institutes of Health
Article History
Received: 29 October 2024
Accepted: 24 February 2025
First Online: 6 June 2025
Change Date: 16 June 2025
Change Type: Update
Change Details: In the original version of this article, in Table 2, a formatting issue resulted in the entry “222 M (38.9%)” under the column “Sex at Birth” appearing across two lines rather than on a single line. This has now been corrected.
Competing interests
: The authors declare the following competing interests: B.H.E. is part of the Advisory Board of Boehringer Ingelheim, Lundbeck Pharma A/S; and has received lecture fees from Boehringer Ingelheim, Otsuka Pharma Scandinavia AB, and Lundbeck Pharma A/S; C.A. has been a consultant to or has received honoraria or grants from Acadia, Angelini, Biogen, Boehringer, Gedeon Richter, Janssen Cilag, Lundbeck, Medscape, Menarini, Minerva, Otsuka, Pfizer, Roche, Sage, Servier, Shire, Schering Plough, Sumitomo Dainippon Pharma, Sunovion and Takeda; C.D.C. has received grant support from Instituto de Salud Carlos III, Spanish Ministry of Science and Innovation and honoraria or travel support from Angelini, Janssen, and Viatris; C.M.C. is an Associate Editor of Nature: Schizophrenia; D.D. has received honorary funds for one educational seminar for CSL Sequiris; D.O.P. has been a consultant to Alkermes; E.Y.H.C. has received speaker fees at non-promotional educational events; GAL has been a consultant for Bristol Myers Squibb, Cerevel, Johnson & Johnson, Neurocrine, NeuroSig, and Sosei-Heptares; J.K. has received speaking or consulting fees from Janssen, Boehringer Ingelheim, ROVI and Lundbeck; J.M.K. is a consultant to or receives honoraria and/or travel support and/or speakers fees from Alkermes, Allergan, Boehringer-Ingelheim, Cerevel, Dainippon Sumitomo, H. Lundbeck, HealthRhythms, HLS Therapeutics, Indivior, Intracellular Therapies, Janssen Pharmaceutical, Johnson & Johnson, Karuna Therapeutics/Bristol Myers Squibb, LB Pharmaceuticals, Mapi, Maplight, Merck, Minerva, Neurocrine, Newron, Novartis, NW PharmaTech, Otsuka, Roche, Saladax, Sunovion, and Teva; and is on Advisory Boards for Alkermes, Boehringer-Ingelheim, Cerevel, Click Therapeutics, Karuna/BMS, Lundbeck, Merck, Newron, Novartis, Otsuka, Sumitomo, Teva, and Terran; and has received grant support from Lundbeck, Janssen, Otsuka, and Sunovion; and has shareholder interest in Cerevel (public/stock), HealthRhythms (private/stock options), Karuna/BMS (public), LB Pharmaceuticals (private/stock options), North Shore Therapeutics (private/stock), and Vanguard Research Group (private/40% owner); P.F.P. has received research funds or personal fees from Lundbeck, Angelini, Menarini, Sunovion, Boehringer Ingelheim, Proxymm Science, Otsuka, outside the current study; R.S.K. has been a consultant to Alkermes and Boehringer-Ingelheim; R.U. has received speaker fees at non-promotional educational event: Otsuka: Consultancy for Viatris and Springer Healthcare. Honorary General Secretary British Association for Psychopharmacology (unpaid); S.W.W. has received speaking fees from the American Psychiatric Association and from Medscape Features. He has been granted US patent No. 8492418 B2 for a method of treating prodromal schizophrenia with glycine agonists. He owns stock in NW PharmaTech; and Z.T. has been a consultant for Manifest Technologies. All other authors report no biomedical financial interests or potential conflicts of interest.