Qu, Yuanhao https://orcid.org/0000-0002-7574-259X
Huang, Kaixuan
Yin, Ming
Zhan, Kanghong
Liu, Dyllan
Yin, Di
Cousins, Henry C.
Johnson, William A.
Wang, Xiaotong
Shah, Mihir https://orcid.org/0000-0003-0854-2384
Altman, Russ B. https://orcid.org/0000-0003-3859-2905
Zhou, Denny
Wang, Mengdi https://orcid.org/0000-0002-2101-9507
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute (R35HG011316, 1R01GM141627)
Donald E. and Delia B. Baxter Foundation
National Science Foundation (1653435)
Article History
Received: 25 June 2024
Accepted: 17 June 2025
First Online: 30 July 2025
Competing interests
: Princeton University and Stanford University have filed patent applications (#19/093,928, Princeton and Stanford, 2025) based on this work, where L.C., M.W., Y.Q. and K.H. are listed as inventors. L.C. is a member of the scientific advisory board of Arbor Biotechnologies. L.C. has equity interest in Auto Bio, Rootpath Genomics, and Acrobat Genomics. D.Z. is an employee of Google DeepMind. The remaining authors declare no competing interests.