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BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2

Crossref DOI link: https://doi.org/10.1038/s41556-021-00821-8

Published Online: 2022-01-13

Published Print: 2022-01

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Samelson, Avi J.

Tran, Quang Dinh https://orcid.org/0000-0002-9263-0733
Robinot, Rémy

Carrau, Lucia

Rezelj, Veronica V.

Kain, Alice Mac https://orcid.org/0000-0002-5218-6690
Chen, Merissa

Ramadoss, Gokul N. https://orcid.org/0000-0002-7506-2711
Guo, Xiaoyan

Lim, Shion A. https://orcid.org/0000-0003-2136-2732
Lui, Irene https://orcid.org/0000-0002-6171-5443
Nuñez, James K.

Rockwood, Sarah J. https://orcid.org/0000-0002-2869-0221
Wang, Jianhui

Liu, Na

Carlson-Stevermer, Jared

Oki, Jennifer

Maures, Travis

Holden, Kevin https://orcid.org/0000-0002-3091-4124
Weissman, Jonathan S. https://orcid.org/0000-0003-2445-670X
Wells, James A. https://orcid.org/0000-0001-8267-5519
Conklin, Bruce R.

TenOever, Benjamin R. https://orcid.org/0000-0003-0324-3078
Chakrabarti, Lisa A. https://orcid.org/0000-0002-1895-3630
Vignuzzi, Marco https://orcid.org/0000-0002-4400-771X
Tian, Ruilin https://orcid.org/0000-0001-7680-6682
Kampmann, Martin https://orcid.org/0000-0002-3819-7019
Funding

Funding for this research was provided by:

U.S. Department of Health & Human Services | NIH | National Institute on Aging (F32 AG063487)

National Science Foundation

Helen Hay Whitney Foundation
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Text and Data Mining valid from 2022-01-01

Version of Record valid from 2022-01-01
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Article History

Received: 18 January 2021

Accepted: 24 November 2021

First Online: 13 January 2022

Competing interests

: J.C.-S., J.O., T.M. and K.H. are employees and shareholders of Synthego Corporation. All other authors declare no competing interests.

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