Khawaja, Rabia R. https://orcid.org/0000-0003-3907-988X
Griego, Ernesto
Lindenau, Kristen https://orcid.org/0000-0001-6145-5322
Salek, Asma
Gambardella, Jessica
Scrivo, Aurora
Monday, Hannah R.
Bourdenx, Mathieu
Madero-Pérez, Jesús
Khan, Zohaib N.
Chavda, Bhakti
Cutler, Ronald
Graff, Sarah
Sidoli, Simone https://orcid.org/0000-0001-9073-6641
Santulli, Gaetano https://orcid.org/0000-0001-7231-375X
Santambrogio, Laura https://orcid.org/0000-0002-4674-7041
Tasset, Inmaculada
Kaushik, Susmita https://orcid.org/0000-0002-6096-5387
Gan, Li https://orcid.org/0000-0003-4600-275X
Castillo, Pablo E. https://orcid.org/0000-0002-9834-1801
Cuervo, Ana Maria https://orcid.org/0000-0002-0771-700X
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute on Aging (AG021904, AG054108, AG031782, T32AG023475, AG031782, AG031782)
JPB Foundation (N/A)
Hevolution Foundation, Boston MA, USA Rainwater Charitable Foundation Fort Worth, TX USA Backus Foundation, New York NY USA
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (K12GM102779)
Hevolution Foundation, Boston MA, USA
U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (DK123259)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (HL146691)
American Heart Association (24IPA1268813)
Grace Science Foundation (N/A)
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (MH125772)
Article History
Received: 10 November 2024
Accepted: 21 August 2025
First Online: 14 October 2025
Competing interests
: A.M.C. is a co-founder and scientific advisor for the autophagy programme at Life Biosciences. The remaining authors declare no competing interests.