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MAPL regulates gasdermin-mediated release of mtDNA from lysosomes to drive pyroptotic cell death

Crossref DOI link: https://doi.org/10.1038/s41556-025-01774-y

Published Online: 2025-10-13

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Nguyen, Mai https://orcid.org/0000-0001-5485-0308
Collier, Jack J. https://orcid.org/0000-0001-6282-0301
Ignatenko, Olesia https://orcid.org/0000-0002-1510-6153
Morin, Genevieve https://orcid.org/0009-0009-6398-9593
Goyon, Vanessa

Janer, Alexandre

Tiefensee Ribeiro, Camila

Milnerwood, Austen J. https://orcid.org/0000-0002-0056-1778
Huang, Sidong

Desjardins, Michel https://orcid.org/0000-0002-5684-5980
McBride, Heidi M. https://orcid.org/0000-0003-4666-2280
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Text and Data Mining valid from 2025-10-13

Version of Record valid from 2025-10-13
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Article History

Received: 7 March 2024

Accepted: 25 August 2025

First Online: 13 October 2025

Competing interests

: The authors declare no competing interests.