Oshio, Hijiri https://orcid.org/0009-0000-4719-8665
Shiiba, Isshin https://orcid.org/0000-0002-8093-1782
Ito, Naoki https://orcid.org/0009-0003-8182-7471
Okada, Naozumi
Yamaguchi, Fuya
Ishikawa, Yuto https://orcid.org/0009-0002-5933-9183
Nagashima, Shun https://orcid.org/0000-0001-8042-0897
Fujikawa, Yuuta https://orcid.org/0000-0002-5872-8462
Umezawa, Keitaro https://orcid.org/0000-0002-2380-4453
Miura, Yuri
Shimizu, Misaki
Saito, Yoshiro https://orcid.org/0000-0002-0559-5889
Yamaguchi, Tomoyuki
Inatome, Ryoko
Yanagi, Shigeru https://orcid.org/0000-0002-1392-8663
Funding for this research was provided by:
Japan Agency for Medical Research and Development (JP20gm5010002 and JP25gm2110001)
MEXT | Japan Society for the Promotion of Science (23K02691, 20H04911 and 20H03454)
MEXT | Japan Society for the Promotion of Science (22K15399, 22H05574, 24H01327, and 24K18382)
MEXT | Japan Society for the Promotion of Science (23K14185 and 22K20637)
MEXT | Japan Society for the Promotion of Science (21K06844)
Uehara Memorial Foundation
Kowa Life Science Foundation
Takeda Medical Research Foundation
Daiichi Sankyo Foundation of Life Science
Article History
Received: 10 September 2025
Accepted: 4 May 2026
First Online: 10 June 2026
Competing interests
: The authors declare no competing interests.