Carlson, Rebecca J.
Patten, J. J. https://orcid.org/0000-0002-9770-7525
Stefanakis, George
Soong, Brian Y. https://orcid.org/0000-0003-4647-7704
Radhakrishnan, Adityanarayanan
Singh, Avtar
Thakur, Naveen https://orcid.org/0009-0008-9537-8423
Sheehan, Kathleen C. F.
Amarasinghe, Gaya K. https://orcid.org/0000-0002-0418-9707
Hacohen, Nir
Basler, Christopher F. https://orcid.org/0000-0003-4195-425X
Leung, Daisy W. https://orcid.org/0000-0002-7189-9557
Uhler, Caroline
Davey, Robert A. https://orcid.org/0000-0001-9168-2892
Blainey, Paul C. https://orcid.org/0000-0002-4889-8783
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (P01AI120943, P01AI120943., P01AI120943, P01AI120943, P01AI120943, P01AI120943, P01AI120943)
Hertz Foundation (01)
NSF | Directorate for Education & Human Resources | Division of Graduate Education (01)
U.S. Department of Health & Human Services | NIH | National Center for Complementary and Integrative Health (1DP2AT012345)
United States Department of Defense | United States Navy | Office of Naval Research (N00014-22-1-2116, N00014-22-1-2116, N00014-22-1-2116)
U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute (HG009283, HG009283, HG006193)
Burroughs Wellcome Fund (Career Award)
Article History
Received: 11 March 2024
Accepted: 15 May 2025
First Online: 24 July 2025
Competing interests
: P.C.B. is a consultant to or holds equity in 10X Genomics, General Automation Lab Technologies/Isolation Bio, Next Gen Diagnostics, Cache DNA, Concerto Biosciences, Stately, Ramona Optics, Bifrost Biosystems, and Amber Bio. His laboratory received research funding from Calico Life Sciences, Merck, and Genentech for work related to genetic screening. N.H. holds equity in and advises Danger Bio/Related Sciences, owns equity in BioNtech and receives research funding from Bristol Myers Squibb. C.U. serves on the Scientific Advisory Board of Immunai, Relation Therapeutics, and Focal Biosciences, and receives research funding from AstraZeneca and Janssen Pharmaceuticals. The Broad Institute and MIT may seek to commercialize aspects of this work, and related applications for intellectual property have been filed. A.S. is an employee at Genentech and R.J.C. is an employee at Flagship Pioneering. The remaining authors declare no competing interests.