Miletic, Sean https://orcid.org/0000-0002-2732-8626
Icho, Simoun
Li, Zhijie
Tam, John
Rose, Elizabeth C.
Perkins, Cypress E. https://orcid.org/0000-0002-8252-7679
Nakhi, Ali
Yang, Xinglin
Hang, Howard C. https://orcid.org/0000-0003-4053-5547
Rubinstein, John L. https://orcid.org/0000-0003-0566-2209
Dosa, Peter I. https://orcid.org/0000-0002-0081-3867
Theriot, Casey M. https://orcid.org/0000-0002-1895-8941
Melnyk, Roman A. https://orcid.org/0000-0002-7187-2362
Funding for this research was provided by:
Hospital for Sick Children
Article History
Received: 25 February 2025
Accepted: 7 October 2025
First Online: 18 November 2025
Competing interests
: C.M.T. has consulted for Vedanta Biosciences, Summit Therapeutics and Ferring Pharmaceuticals and is on the Scientific Advisory Board for Ancilia Biosciences. R.A.M. has consulted for Sanofi and Spotlight Therapeutics and is on the Scientific Advisory Board for Adaxion Therapeutics. The other authors declare no competing interests.