Rudra, Arnab https://orcid.org/0000-0002-1704-5534
Gupta, Akash https://orcid.org/0000-0001-5614-2313
Reed, Kaelan https://orcid.org/0000-0002-0082-1613
Deik, Amy https://orcid.org/0000-0002-9687-0953
Min, Jiyeon https://orcid.org/0009-0006-8086-095X
Mansour, Hasan Mansour A https://orcid.org/0000-0002-1422-5062
Nguyen, Quang Trung Chinh https://orcid.org/0009-0006-6007-1988
Danko, Austin
Hu, Yizong
Berger, Allegra
Prado, Michaela https://orcid.org/0000-0002-1024-7176
Beck, Amira
Clish, Clary B.
Klauda, Jeffery B. https://orcid.org/0000-0001-8725-1870
Langer, Robert https://orcid.org/0000-0003-4255-0492
Anderson, Daniel G. https://orcid.org/0000-0001-5629-4798
Funding for this research was provided by:
Sanofi
U.S. Department of Health & Human Services | NIH | National Cancer Institute (5P30-CA014051)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (5P30-CA014051)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (5P30-CA014051)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (5P30-CA014051)
U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (R61AI161805)
U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (R61AI161805)
U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (R61AI161805)
Article History
Received: 2 January 2025
Accepted: 24 September 2025
First Online: 7 November 2025
Competing interests
: D.G.A. discloses potential competing interests due to his advising (past and present), Alnylam, Sanofi, Translate Bio, oRNA Therapeutics and Combined Therapeutics. R.L. discloses potential competing interests due to his advising (past and present) Alnylam, Moderna and Combined Therapeutics. For a list of entities with which R.L. is involved, compensated or uncompensated, see . Patent applications covering aspects of this work have been filed by D.G.A., A.R., A.G. and K.R. with application numbers 18/396,181 and 63/614,873, and are currently pending. The other authors declare no competing interests.