Tran, Quang-Dinh https://orcid.org/0000-0002-9263-0733
Vignuzzi, Marco https://orcid.org/0000-0002-4400-771X
Article History
Accepted: 28 April 2026
First Online: 14 May 2026
Competing interests
: This Review cites some of the works performed by the authors, including the following works for which M.V. is an inventor on the following patents: ‘RNA virus attenuation by alteration of mutational robustness and sequence space’, US patent number US20180008689A1; ‘Defective Interfering Viral Genomes’, US patent application US20230174953A1; and ‘Therapeutic Defective Interfering Particles’ US patent application 63/903,970. M.V.’s lab at A*STAR has also signed a collaborative agreement with Apriori Bio, a vaccine company that uses artificial intelligence and experimental data to predict viral evolution and vaccine performance.