Lu, Yuancheng http://orcid.org/0000-0002-5982-3963
Brommer, Benedikt
Tian, Xiao http://orcid.org/0000-0001-5300-3596
Krishnan, Anitha
Meer, Margarita
Wang, Chen
Vera, Daniel L.
Zeng, Qiurui
Yu, Doudou
Bonkowski, Michael S.
Yang, Jae-Hyun
Zhou, Songlin
Hoffmann, Emma M.
Karg, Margarete M.
Schultz, Michael B.
Kane, Alice E.
Davidsohn, Noah http://orcid.org/0000-0002-4470-5665
Korobkina, Ekaterina
Chwalek, Karolina
Rajman, Luis A.
Church, George M. http://orcid.org/0000-0003-3535-2076
Hochedlinger, Konrad http://orcid.org/0000-0001-5811-5386
Gladyshev, Vadim N. http://orcid.org/0000-0002-0372-7016
Horvath, Steve http://orcid.org/0000-0002-4110-3589
Levine, Morgan E.
Gregory-Ksander, Meredith S.
Ksander, Bruce R. http://orcid.org/0000-0001-5546-0360
He, Zhigang http://orcid.org/0000-0001-6080-6880
Sinclair, David A. http://orcid.org/0000-0002-9936-436X
Article History
Received: 31 July 2019
Accepted: 22 October 2020
First Online: 2 December 2020
Competing interests
: D.A.S. is a consultant to, inventor of patents licensed to, board member of and equity owner of Iduna Therapeutics, a Life Biosciences company developing epigenetic reprograming therapies. D.A.S. is an advisor to Zymo Research, an epigenetics tools company. Additional disclosures are atExternalRef removed. Y.L., L.A.R. and S.H. are equity owners of Iduna Therapeutics, a Life Biosciences company. D.L.V. is an advisor to Liberty Biosecurity. M.S.B. is a shareholder in MetroBiotech. K.C. is an equity owner in Life Biosciences and affiliates. N.D. and G.M.C. are co-founders of Rejuvenate Bio. Disclosures for G.M.C. can be found atExternalRef removed. M.E.L. is a bioinformatics advisor to Elysium Health. Y.L., N.D. and D.A.S. are inventors on patents arising from this work (WO/2020/069373 and WO/2020/069339), filed by the President and Fellows of Harvard College. The other authors declare no competing interests.