Lu, Yuancheng https://orcid.org/0000-0002-5982-3963
Brommer, Benedikt
Tian, Xiao https://orcid.org/0000-0001-5300-3596
Krishnan, Anitha
Meer, Margarita
Wang, Chen
Vera, Daniel L.
Zeng, Qiurui
Yu, Doudou
Bonkowski, Michael S.
Yang, Jae-Hyun
Zhou, Songlin
Hoffmann, Emma M.
Karg, Margarete M.
Schultz, Michael B.
Kane, Alice E.
Davidsohn, Noah https://orcid.org/0000-0002-4470-5665
Korobkina, Ekaterina
Chwalek, Karolina
Rajman, Luis A.
Church, George M. https://orcid.org/0000-0003-3535-2076
Hochedlinger, Konrad https://orcid.org/0000-0001-5811-5386
Gladyshev, Vadim N. https://orcid.org/0000-0002-0372-7016
Horvath, Steve https://orcid.org/0000-0002-4110-3589
Levine, Morgan E.
Gregory-Ksander, Meredith S.
Ksander, Bruce R. https://orcid.org/0000-0001-5546-0360
He, Zhigang https://orcid.org/0000-0001-6080-6880
Sinclair, David A. https://orcid.org/0000-0002-9936-436X
Article History
Received: 31 July 2019
Accepted: 22 October 2020
First Online: 2 December 2020
Competing interests
: D.A.S. is a consultant to, inventor of patents licensed to, board member of and equity owner of Iduna Therapeutics, a Life Biosciences company developing epigenetic reprograming therapies. D.A.S. is an advisor to Zymo Research, an epigenetics tools company. Additional disclosures are at . Y.L., L.A.R. and S.H. are equity owners of Iduna Therapeutics, a Life Biosciences company. D.L.V. is an advisor to Liberty Biosecurity. M.S.B. is a shareholder in MetroBiotech. K.C. is an equity owner in Life Biosciences and affiliates. N.D. and G.M.C. are co-founders of Rejuvenate Bio. Disclosures for G.M.C. can be found at . M.E.L. is a bioinformatics advisor to Elysium Health. Y.L., N.D. and D.A.S. are inventors on patents arising from this work (WO/2020/069373 and WO/2020/069339), filed by the President and Fellows of Harvard College. The other authors declare no competing interests.