Kurki, Mitja I.
Karjalainen, Juha
Palta, Priit
Sipilä, Timo P.
Kristiansson, Kati
Donner, Kati M.
Reeve, Mary P.
Laivuori, Hannele
Aavikko, Mervi
Kaunisto, Mari A.
Loukola, Anu
Lahtela, Elisa
Mattsson, Hannele
Laiho, Päivi
Della Briotta Parolo, Pietro
Lehisto, Arto A.
Kanai, Masahiro
Mars, Nina
Rämö, Joel
Kiiskinen, Tuomo
Heyne, Henrike O.
Veerapen, Kumar
Rüeger, Sina
Lemmelä, Susanna
Zhou, Wei
Ruotsalainen, Sanni
Pärn, Kalle
Hiekkalinna, Tero
Koskelainen, Sami
Paajanen, Teemu
Llorens, Vincent
Gracia-Tabuenca, Javier
Siirtola, Harri
Reis, Kadri
Elnahas, Abdelrahman G.
Sun, Benjamin
Foley, Christopher N.
Aalto-Setälä, Katriina
Alasoo, Kaur
Arvas, Mikko
Auro, Kirsi
Biswas, Shameek
Bizaki-Vallaskangas, Argyro
Carpen, Olli
Chen, Chia-Yen
Dada, Oluwaseun A.
Ding, Zhihao
Ehm, Margaret G.
Eklund, Kari
Färkkilä, Martti
Finucane, Hilary
Ganna, Andrea
Ghazal, Awaisa
Graham, Robert R.
Green, Eric M.
Hakanen, Antti
Hautalahti, Marco
Hedman, Åsa K.
Hiltunen, Mikko
Hinttala, Reetta
Hovatta, Iiris
Hu, Xinli
Huertas-Vazquez, Adriana
Huilaja, Laura
Hunkapiller, Julie
Jacob, Howard
Jensen, Jan-Nygaard
Joensuu, Heikki
John, Sally
Julkunen, Valtteri
Jung, Marc
Junttila, Juhani
Kaarniranta, Kai
Kähönen, Mika
Kajanne, Risto
Kallio, Lila
Kälviäinen, Reetta
Kaprio, Jaakko
,
Kerimov, Nurlan
Kettunen, Johannes
Kilpeläinen, Elina
Kilpi, Terhi
Klinger, Katherine
Kosma, Veli-Matti
Kuopio, Teijo
Kurra, Venla
Laisk, Triin
Laukkanen, Jari
Lawless, Nathan
Liu, Aoxing
Longerich, Simonne
Mägi, Reedik
Mäkelä, Johanna
Mäkitie, Antti
Malarstig, Anders
Mannermaa, Arto
Maranville, Joseph
Matakidou, Athena
Meretoja, Tuomo
Mozaffari, Sahar V.
Niemi, Mari E. K.
Niemi, Marianna
Niiranen, Teemu
O´Donnell, Christopher J.
Obeidat, Ma´en
Okafo, George
Ollila, Hanna M.
Palomäki, Antti
Palotie, Tuula
Partanen, Jukka
Paul, Dirk S.
Pelkonen, Margit
Pendergrass, Rion K.
Petrovski, Slavé
Pitkäranta, Anne
Platt, Adam
Pulford, David
Punkka, Eero
Pussinen, Pirkko
Raghavan, Neha
Rahimov, Fedik
Rajpal, Deepak
Renaud, Nicole A.
Riley-Gillis, Bridget
Rodosthenous, Rodosthenis
Saarentaus, Elmo
Salminen, Aino
Salminen, Eveliina
Salomaa, Veikko
Schleutker, Johanna
Serpi, Raisa
Shen, Huei-yi
Siegel, Richard
Silander, Kaisa
Siltanen, Sanna
Soini, Sirpa
Soininen, Hilkka
Sul, Jae Hoon
Tachmazidou, Ioanna
Tasanen, Kaisa
Tienari, Pentti
Toppila-Salmi, Sanna
Tukiainen, Taru
Tuomi, Tiinamaija
Turunen, Joni A.
Ulirsch, Jacob C.
Vaura, Felix
Virolainen, Petri
Waring, Jeffrey
Waterworth, Dawn
Yang, Robert
Nelis, Mari
Reigo, Anu
Metspalu, Andres
Milani, Lili
Esko, Tõnu
Fox, Caroline
Havulinna, Aki S.
Perola, Markus
Ripatti, Samuli
Jalanko, Anu
Laitinen, Tarja
Mäkelä, Tomi P.
Plenge, Robert
McCarthy, Mark
Runz, Heiko
Daly, Mark J.
Palotie, Aarno http://orcid.org/0000-0002-2527-5874
Article History
Received: 10 January 2022
Accepted: 21 October 2022
First Online: 18 January 2023
Change Date: 24 February 2023
Change Type: Correction
Change Details: A Correction to this paper has been published:
Change Details: https://doi.org/10.1038/s41586-023-05837-8
Competing interests
: J.C.U.: has received compensation for consulting from Goldfinch Bio and is an employee of Patch Biosciences. K.E.: Consultation fees from Sobi, and Orion corporation. A. Palomäki: consulting fee from Abbvie, Amgen and Pfizer, lecture fee from Pfizer and Sanofi. H. Jacob: employee of AbbVie. F.R.: employee of AbbVie. B.R.-G.: employee of AbbVie. J.W.: employee of AbbVie. A. Matakidou: employee of AstraZeneca. D.S.P.: employee of AstraZeneca. S.P.: employee of AstraZeneca. A. Platt: employee of AstraZeneca. I.T.: employee of AstraZeneca. B.S.: employee of Biogen. C.-Y.C.: employee of Biogen. S.J.: employee of Biogen. H.R.: employee of Biogen. Z.D.: employee of Boehringer Ingelheim. J.-N.J.: employee of Boehringer Ingelheim. M.J.: employee of Boehringer Ingelheim. N.L.: employee of Boehringer Ingelheim. G.O.: employee of Boehringer Ingelheim. S.B.: employee of Bristol Myers Squibb. J. Maranville: employee of Bristol Myers Squibb. R.P.: employee of Bristol Myers Squibb. J.H.: employee of Genentech. R.K.P.: employee of Genentech. M.M.: employee of Genentech. K. Auro: employee of GlaxoSmithKline. M.G.E.: employee of GlaxoSmithKline. D.P.: employee of GlaxoSmithKline. R.Y.: employee of Janssen Biotech. D.W.: employee of Janssen Research & Development. R.R.G.: employee of Maze Therapeutics. E.M.G.: employee of Maze Therapeutics. S.V.M.: employee of Maze Therapeutics. A.H.-V.: employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA. S. Longerich: employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA. N.R.: employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA. J.H.S.: employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA. C.F.: employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA. M.E.K.N.: employee of Novartis. C.J.O.: employee of Novartis. M.O.: employee of Novartis. N.R.: employee of Novartis. R. Siegel: employee of Novartis. Å.K.H.: employee of Pfizer. X.H.: employee of Pfizer. A. Malarstig: employee of Pfizer. K. Klinger: employee of Sanofi. D.R.: employee of Sanofi. J.P.: employee of the Finnish Red Cross Blood Service. A.G.E.: employee of University of Tartu. M.J.D.: founder of Maze Therapeutics. T. Kuopio: lecture fee from Amgen, Roche and MSD. J.A.T.: lecture fee from Blueprint Genetics Finland, and on the advisory board of Novartis Finland (unrelated to this work). P.T.: lecture or consulting fee from Alexion, Roche, Merck, Janssen-Cilag, Novartis and Biogen (unrelated to this work). M. Aavikko: lecturing fee and congress trip reimbursement from Ipsen and Novartis (unrelated to this work). A. Palotie: member of the Pfizer Genetics Scientific Advisory Panel. V.S.: received a honorarium from Sanofi for consulting, and ongoing research collaboration with Bayer (all unrelated to the present study). H. Joensuu: senior consultant for Orion Pharma Orion, Chairman of the Scientific Advisory Board in Neutron Therapeutics, received a fee for acting as the Chair of an ESMO meeting from Deciphera Pharmaceuticals, stock ownership in Orion Pharma and Sartar Therapeutics. The other authors declare no competing interests.