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Authors
Martínez-Ruiz, Carlos https://orcid.org/0000-0002-4817-0565
Black, James R. M.
Puttick, Clare
Hill, Mark S. https://orcid.org/0000-0003-0718-8934
Demeulemeester, Jonas https://orcid.org/0000-0002-2660-2478
Larose Cadieux, Elizabeth https://orcid.org/0000-0002-9320-8040
Thol, Kerstin https://orcid.org/0000-0002-4624-118X
Jones, Thomas P.
Veeriah, Selvaraju
Naceur-Lombardelli, Cristina
Toncheva, Antonia
Prymas, Paulina
Rowan, Andrew
Ward, Sophia https://orcid.org/0000-0002-6777-5279
Cubitt, Laura
Athanasopoulou, Foteini
Pich, Oriol https://orcid.org/0000-0002-1956-1882
Karasaki, Takahiro https://orcid.org/0000-0001-6863-2360
Moore, David A. https://orcid.org/0000-0002-6296-1312
Salgado, Roberto https://orcid.org/0000-0002-1110-3801
Colliver, Emma https://orcid.org/0000-0002-1497-0740
Castignani, Carla
Dietzen, Michelle https://orcid.org/0000-0002-6853-7563
Huebner, Ariana https://orcid.org/0000-0001-8009-4999
Al Bakir, Maise https://orcid.org/0000-0002-0846-8332
Tanić, Miljana https://orcid.org/0000-0003-3102-776X
Watkins, Thomas B. K.
Lim, Emilia L.
Al-Rashed, Ali M. https://orcid.org/0000-0003-4280-1677
Lang, Danny
Clements, James https://orcid.org/0000-0002-7837-7807
Cook, Daniel E. https://orcid.org/0000-0003-3347-562X
Rosenthal, Rachel
Wilson, Gareth A.
Frankell, Alexander M. https://orcid.org/0000-0002-0341-7878
de Carné Trécesson, Sophie
East, Philip https://orcid.org/0000-0001-5801-5713
Kanu, Nnennaya
Litchfield, Kevin
Birkbak, Nicolai J. https://orcid.org/0000-0003-1613-9587
Hackshaw, Allan https://orcid.org/0000-0002-5570-5070
Beck, Stephan https://orcid.org/0000-0001-5290-2151
Van Loo, Peter https://orcid.org/0000-0003-0292-1949
Jamal-Hanjani, Mariam https://orcid.org/0000-0003-1212-1259
,
McGranahan, Nicholas
Swanton, Charles
Bakir, Maise Al
Lim, Emilia L.
Frankell, Alexander M.
Litchfield, Kevin
Birkbak, Nicolai J.
Van Loo, Peter
Lester, Jason F.
Bajaj, Amrita
Nakas, Apostolos
Sodha-Ramdeen, Azmina
Ang, Keng
Tufail, Mohamad
Chowdhry, Mohammed Fiyaz
Scotland, Molly
Boyles, Rebecca
Rathinam, Sridhar
Wilson, Claire
Marrone, Domenic
Dulloo, Sean
Fennell, Dean A.
Matharu, Gurdeep
Shaw, Jacqui A.
Riley, Joan
Primrose, Lindsay
Boleti, Ekaterini
Cheyne, Heather
Khalil, Mohammed
Richardson, Shirley
Cruickshank, Tracey
Price, Gillian
Kerr, Keith M.
Benafif, Sarah
Gilbert, Kayleigh
Naidu, Babu
Patel, Akshay J.
Osman, Aya
Lacson, Christer
Langman, Gerald
Shackleford, Helen
Djearaman, Madava
Kadiri, Salma
Middleton, Gary
Leek, Angela
Hodgkinson, Jack Davies
Totten, Nicola
Montero, Angeles
Smith, Elaine
Fontaine, Eustace
Granato, Felice
Doran, Helen
Novasio, Juliette
Rammohan, Kendadai
Joseph, Leena
Bishop, Paul
Shah, Rajesh
Moss, Stuart
Joshi, Vijay
Crosbie, Philip
Gomes, Fabio
Brown, Kate
Carter, Mathew
Chaturvedi, Anshuman
Priest, Lynsey
Oliveira, Pedro
Lindsay, Colin R.
Blackhall, Fiona H.
Krebs, Matthew G.
Summers, Yvonne
Clipson, Alexandra
Tugwood, Jonathan
Kerr, Alastair
Rothwell, Dominic G.
Kilgour, Elaine
Dive, Caroline
Aerts, Hugo J. W. L.
Schwarz, Roland F.
Kaufmann, Tom L.
Szallasi, Zoltan
Kisistok, Judit
Sokac, Mateo
Diossy, Miklos
Bunkum, Abigail
Stewart, Aengus
Magness, Alastair
Karamani, Angeliki
Chain, Benny
Campbell, Brittany B.
Bailey, Chris
Abbosh, Christopher
Weeden, Clare E.
Lee, Claudia
Richard, Corentin
Hiley, Crispin T.
Pearce, David R.
Karagianni, Despoina
Biswas, Dhruva
Levi, Dina
Hoxha, Elena
Nye, Emma
Grönroos, Eva
Gálvez-Cancino, Felip
Gimeno-Valiente, Francisco
Kassiotis, George
Stavrou, Georgia
Mastrokalos, Gerasimos
Zhai, Haoran
Lowe, Helen L.
Matos, Ignacio Garcia
Goldman, Jacki
Reading, James L.
Herrero, Javier
Rane, Jayant K.
Nicod, Jerome
Lam, Jie Min
Hartley, John A.
Peggs, Karl S.
Enfield, Katey S. S.
Selvaraju, Kayalvizhi
Ng, Kevin W.
Chen, Kezhong
Dijkstra, Krijn
Grigoriadis, Kristiana
Thakkar, Krupa
Ensell, Leah
Shah, Mansi
Duran, Marcos Vasquez
Litovchenko, Maria
Sunderland, Mariana Werner
Leung, Michelle
Escudero, Mickael
Angelova, Mihaela
Sivakumar, Monica
Chervova, Olga
Lucas, Olivia
Al-Sawaf, Othman
Hobson, Philip
Pawlik, Piotr
Stone, Richard Kevin
Bentham, Robert
Hynds, Robert E.
Vendramin, Roberto
Saghafinia, Sadegh
López, Saioa
Gamble, Samuel
Ung, Seng Kuong Anakin
Quezada, Sergio A.
Vanloo, Sharon
Zaccaria, Simone
Hessey, Sonya
Boeing, Stefan
Bola, Supreet Kaur
Denner, Tamara
Marafioti, Teresa
Mourikis, Thanos P.
Spanswick, Victoria
Barbè, Vittorio
Lu, Wei-Ting
Hill, William
Liu, Wing Kin
Wu, Yin
Naito, Yutaka
Ramsden, Zoe
Veiga, Catarina
Royle, Gary
Collins-Fekete, Charles-Antoine
Fraioli, Francesco
Ashford, Paul
Clark, Tristan
Forster, Martin D.
Lee, Siow Ming
Borg, Elaine
Falzon, Mary
Papadatos-Pastos, Dionysis
Wilson, James
Ahmad, Tanya
Procter, Alexander James
Ahmed, Asia
Taylor, Magali N.
Nair, Arjun
Lawrence, David
Patrini, Davide
Navani, Neal
Thakrar, Ricky M.
Janes, Sam M.
Hoogenboom, Emilie Martinoni
Monk, Fleur
Holding, James W.
Choudhary, Junaid
Bhakhri, Kunal
Scarci, Marco
Hayward, Martin
Panagiotopoulos, Nikolaos
Gorman, Pat
Khiroya, Reena
Stephens, Robert C. M.
Wong, Yien Ning Sophia
Bandula, Steve
Sharp, Abigail
Smith, Sean
Gower, Nicole
Dhanda, Harjot Kaur
Chan, Kitty
Pilotti, Camilla
Leslie, Rachel
Grapa, Anca
Zhang, Hanyun
AbdulJabbar, Khalid
Pan, Xiaoxi
Yuan, Yinyin
Chuter, David
MacKenzie, Mairead
Chee, Serena
Alzetani, Aiman
Cave, Judith
Scarlett, Lydia
Richards, Jennifer
Ingram, Papawadee
Austin, Silvia
Lim, Eric
De Sousa, Paulo
Jordan, Simon
Rice, Alexandra
Raubenheimer, Hilgardt
Bhayani, Harshil
Ambrose, Lyn
Devaraj, Anand
Chavan, Hema
Begum, Sofina
Buderi, Silviu I.
Kaniu, Daniel
Malima, Mpho
Booth, Sarah
Nicholson, Andrew G.
Fernandes, Nadia
Shah, Pratibha
Proli, Chiara
Hewish, Madeleine
Danson, Sarah
Shackcloth, Michael J.
Robinson, Lily
Russell, Peter
Blyth, Kevin G.
Dick, Craig
Le Quesne, John
Kirk, Alan
Asif, Mo
Bilancia, Rocco
Kostoulas, Nikos
Thomas, Mathew
Swanton, Charles https://orcid.org/0000-0002-4299-3018
McGranahan, Nicholas https://orcid.org/0000-0001-9537-4045
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Article History
Received: 21 October 2021
Accepted: 4 January 2023
First Online: 12 April 2023
Competing interests
: S.V. is a co-inventor to a patent to detect molecules in a sample (US patent no. 10578620). M.A.B. has consulted for Achilles Therapeutics. A.M.F. is co-inventor to a patent application to determine methods and systems for tumour monitoring (PCT/EP2022/077987). M.J-H. has consulted for, and is a member of, the Achilles Therapeutics Scientific Advisory Board and Steering Committee; has received speaker honoraria from Pfizer, Astex Pharmaceuticals and Oslo Cancer Cluster; and holds patent PCT/US2017/028013 relating to methods for lung cancer detection. This patent has been licensed to commercial entities and under terms of employment. M.J.-H. is due a share of any revenue generated from such license(s). A. Hackshaw has received fees for being a member of independent data monitoring committees for Roche-sponsored clinical trials and academic projects co-ordinated by Roche. C.S. acknowledges grant support from AstraZeneca, Boehringer-Ingelheim, Bristol Myers Squibb, Pfizer, Roche-Ventana, Invitae (previously Archer Dx Inc — collaboration in minimal residual disease sequencing technologies) and Ono Pharmaceutical. C.S. is an AstraZeneca Advisory Board member and chief investigator for the AZ MeRmaiD 1 and 2 clinical trials, and is also co-chief investigator of the NHS Galleri trial, funded by GRAIL, and a paid member of GRAIL’s Scientific Advisory Board. He receives consultant fees from Achilles Therapeutics (where he is also a Scientific Advisory Board member), Bicycle Therapeutics (where he is also a Scientific Advisory Board member), Genentech, Medicxi, Roche Innovation Centre – Shanghai, Metabomed (until July 2022) and the Sarah Cannon Research Institute, had stock options in Apogen Biotechnologies and GRAIL until June 2021, currently has stock options in Epic Bioscience and Bicycle Therapeutics, and has stock options in and is co-founder of Achilles Therapeutics. C.S. is an inventor on a European patent application relating to assay technology to detect tumour recurrence (PCT/GB2017/053289); the patent has been licensed to commercial entities and under his terms of employment C.S is due a revenue share of any revenue generated from such license(s). C.S. holds patents relating to targeting neoantigens (PCT/EP2016/059401), identifying clinical response to immune checkpoint blockade (PCT/EP2016/071471), determining HLA loss of heterozygosity (PCT/GB2018/052004), predicting survival rates of patients with cancer (PCT/GB2020/050221), identifying patients whose cancer responds to treatment (PCT/GB2018/051912), detecting tumour mutations (PCT/US2017/28013), methods for lung cancer detection (US20190106751A1) and identifying insertion/deletion mutation targets (European and US, PCT/GB2018/051892), and is co-inventor to a patent application to determine methods and systems for tumour monitoring (PCT/EP2022/077987). C.S. is a named inventor on a provisional patent protection related to a ctDNA detection algorithm. G.A.W. is employed by and has stock options in Achilles Therapeutics. N.M. has received consultancy fees and has stock options in Achilles Therapeutics. N.M. holds European patents relating to targeting neoantigens (PCT/EP2016/ 059401), identifying clinical response to immune checkpoint blockade (PCT/ EP2016/071471), determining HLA loss of heterozygosity (PCT/GB2018/052004) and predicting survival rates of patients with cancer (PCT/GB2020/050221). D.A.M. reports speaker fees from AstraZeneca, Eli Lilly and Takeda, consultancy fees from AstraZeneca, Thermo Fisher, Takeda, Amgen, Janssen and Eli Lilly and has received educational support from Takeda and Amgen. S.C.T. has acted as a consultant for Revolution Medicines. N.J.B. is a co-inventor to a patent to identify patients whose cancer responds to treatment (PCT/GB2018/051912), a co-inventor on a patent for methods for predicting anti-cancer response (US14/466,208) and has a patent application (PCT/GB2020/050221) on methods for cancer prognostication. R.S. reports non-financial support from Merck and Bristol Myers Squibb (BMS); research support from Merck, Puma Biotechnology and Roche; and personal fees from Roche, BMS and Exact Sciences for advisory boards. E.L.C. is employed by and has stocks in Achilles Therapeutics.
